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Paroxysmal Nocturnal Hemoglobinuria Presenting as Recurrent Jejunitis
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재발성 공장염으로 나타난 발작성 야간혈색소뇨증 1예

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Type
Academic journal
Author
Journal
The Korean Association Of Internal Medicine 대한내과학회지 대한내과학회지 제90권 제2호 KCI Candidated Journals
Published
2016.1
Pages
132 - 135 (4page)

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Paroxysmal Nocturnal Hemoglobinuria Presenting as Recurrent Jejunitis
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Abstract· Keywords

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Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematopoietic stem cell disorder characterized by chronic complement-mediated intravascular hemolysis, nocturnal hemoglobinuria, predisposition to thrombosis and secondary bone marrow failure. Small bowel ischemia is a complication of PNH but has not been reported to date in a Korean adult. We report here a case of PNH presenting as recurrent jejunitis. Despite the uncommon etiology, PNH should be considered in the differential diagnosis of patients with unexplained recurrent jejunitis.
#공장염 #발작성 야간혈색소뇨증 #혈전증 #소장 허혈 #Jejunitis #Paroxysmal nocturnal hemoglobinuria #Thrombosis #Small bowel ischemia

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References (10)

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Wada F / 2000 / Chronic nonspecific jejunitis-A case report- / Acta Med Nagasaki 45:53~56 google schola Gunasekaran TS / 2000 / Duodenojejunitis : is it idiopathic or is it Henoch-Schönlein purpura without the purpura? / J Pediatr Gastroenterol Nutr 30:22~28 google schola Takeda J / 1993 / Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria / Cell 73:703~711 google schola Risitano AM / 2008 / Paroxysmal nocturnal hemoglobinuria : pathophysiology, natural history and treatment options in the era of biological agents / Biologics 2:205~222 google schola Hillmen P / 1995 / Natural history of paroxysmal nocturnal hemoglobinuria / N Engl J Med 333:1253~1258 google schola

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