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초록· 키워드
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The World Health Organization (WHO) Classification of Tumors of Haematopoietic and Lymphoid Tissues was recently published in a revised fourth edition. The categories of myeloproliferative neoplasms (MPNs) have not significantly changed since the 2008 fourth edition of the classification; however, newly discovered mutations including CALR and CSF3R and improved characterizations and standardizations of morphological features of some entities, particularly BCR-ABL1-negative MPNs, have impacted the diagnostic criteria of disease entities, increasing the reliability and reproducibility of diagnoses. The 2017 revised edition attempts to incorporate new clinical, prognostic, morphologic, and genetic data that have emerged since the last edition. This article reviews the major changes in the classification and their rationale for MPN classification within the revised 2017 WHO system.
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참고문헌 (36)
참고문헌 신청
Swerdlow SH / 2017 / WHO classification of tumours of haematopoietic and lymphoid tissues / IARC Press
Tefferi A / 2014 / Long-term survival and blast transformation in molecularly annotated essential thrombocythemia, polycythemia vera, and myelofibrosis / Blood 124:2507~2513
Tefferi A / 2014 / An overview on CALR and CSF3R mutations and a proposal for revision of WHO diagnostic criteria for myeloproliferative neoplasms / Leukemia 28:1407~1413
Barbui T / 2016 / Myeloproliferative neoplasms: morphology and clinical practice / Am J Hematol 91:430~433
Gianelli U / 2014 / Reproducibility of the WHO histological criteria for the diagnosis of Philadelphia chromosome-negative myeloproliferative neoplasms / Mod Pathol 27:814~822
Tefferi A / 2014 / Long-term survival and blast transformation in molecularly annotated essential thrombocythemia, polycythemia vera, and myelofibrosis / Blood 124:2507~2513
Tefferi A / 2014 / An overview on CALR and CSF3R mutations and a proposal for revision of WHO diagnostic criteria for myeloproliferative neoplasms / Leukemia 28:1407~1413
Barbui T / 2016 / Myeloproliferative neoplasms: morphology and clinical practice / Am J Hematol 91:430~433
Gianelli U / 2014 / Reproducibility of the WHO histological criteria for the diagnosis of Philadelphia chromosome-negative myeloproliferative neoplasms / Mod Pathol 27:814~822
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