지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Valproic acid is an effective anticonvulsant used in neurology and psychiatry. Valproic acid-induced hyperammonemic encephalopathy is an unusual complication characterized by a decreasing level of consciousness, the development of progressive confusional states and, sometimes, a coexisting increase in the frequency of seizures after the onset of valproic acid treatment. It can lead to death, but can be reversed if a swift diagnosis is made. We report the case of a 58-year-old woman with an intracerebral hemorrhage and normal liver function who presented with valproic acid-induced hyperammonemic encephalopathy. After valproic acid treatment, she developed encephalopathy and became comatose, with seizures and a markedly elevated serum ammonia level. Her neurologic manifestations and hyperammonemia improved after discontinuing the valproic acid. (Korean J Med 75:680-684, 2008)
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Gomceli YB / 2007 / Different clinical manifestations of hyperammonemic encephalopathy / Epilepsy Behav 10 : 583 ~ 587
Hamer HM / 2000 / Valproateinduced hyperammonemic encephalopathy in the presence of topiramate / Neurology 54 : 230 ~ 232
Ji YJ / 2003 / A case of valproate induced hyperammonemic encephalopathy / J Korean Neuropsychiatr Assoc 42 : 784 ~ 788
Kifune A / 2000 / Valproic acid-induced hyperammonemic encephalopathy with triphasic waves / Epilepsia 41 : 909 ~ 912
Liaw CC / 1999 / Risk of transient hyperammonemic encephalopathy in cancer patients who received continuous infusion of 5-fluorouracil with the complication of dehydration an
Hamer HM / 2000 / Valproateinduced hyperammonemic encephalopathy in the presence of topiramate / Neurology 54 : 230 ~ 232
Ji YJ / 2003 / A case of valproate induced hyperammonemic encephalopathy / J Korean Neuropsychiatr Assoc 42 : 784 ~ 788
Kifune A / 2000 / Valproic acid-induced hyperammonemic encephalopathy with triphasic waves / Epilepsia 41 : 909 ~ 912
Liaw CC / 1999 / Risk of transient hyperammonemic encephalopathy in cancer patients who received continuous infusion of 5-fluorouracil with the complication of dehydration an
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