지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 333 - 337 (5page)
이용수
초록· 키워드
오류제보하기
Background: Uric acid has been reported to function both as an oxidant or antioxidant depending on the context.
A previous study in the Korean population reported a positive linear association between serum uric acid level andarterial stiffness in men, but little is known about how serum uric acid level is related to the risk of increased arterialstiffness in Korean postmenopausal women.
Methods: We performed a cross-sectional study of 293 subjects who participated in a health examination programrun by the health promotion center of Gangnam Severance Hospital between October 2007 and July 2010. Highbrachial-ankle pulse wave velocity was defined as a brachial-ankle pulse wave velocity of more than 1,450 cm/s.
The odds ratios (ORs) for high brachial-ankle pulse wave velocity were calculated using multivariate logistic regressionanalysis across uric acid quartiles after adjusting for other indicators of cardiovascular risk.
Results: The 293 postmenopausal women were divided into quartiles according to uric acid level. The mean brachial-ankle pulse wave velocity values of each quartile were as follows: Q1, 1,474 cm/s; Q2, 1,375 cm/s; Q3, 1,422cm/s; Q4, 1,528 cm/s. The second quartile was designated as the control group based on mean brachial-anklepulse wave velocity value. Multivariate adjusted ORs (95% confidence intervals) for brachial-ankle pulse wave velocityacross the uric acid quartiles were 2.642 (Q1, 1.095–6.3373), 1.00, 4.305 (Q3, 1.798–10.307), and 4.375 (Q4,1.923–9.949), after adjusting for confounding variables.
Conclusion: Serum uric acid level has a J-shaped association with arterial stiffness in Korean postmenopausalwomen.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Ama Moor VJ / 2016 / Assessment of the 10-year risk of cardiovascular events among a group of Sub-Saharan African post-menopausal women / Cardiol J 23 : 123 ~ 131
Au A / 2016 / Estrogens, inflammation and cognition / Front Neuroendocrinol 40 : 87 ~ 100
Becker BF / 1993 / Towards the physiological function of uric acid / Free Radic Biol Med 14 : 615 ~ 631
Boutouyrie P / 2002 / Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients : a longitudinal study / Hypertension 39 : 10 ~ 15
Campesi I / 2016 / Ageing/menopausal status in healthy women and ageing in healthy men differently affect cardiometabolic parameters / Int J Med Sci 13 : 124 ~ 132
Au A / 2016 / Estrogens, inflammation and cognition / Front Neuroendocrinol 40 : 87 ~ 100
Becker BF / 1993 / Towards the physiological function of uric acid / Free Radic Biol Med 14 : 615 ~ 631
Boutouyrie P / 2002 / Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients : a longitudinal study / Hypertension 39 : 10 ~ 15
Campesi I / 2016 / Ageing/menopausal status in healthy women and ageing in healthy men differently affect cardiometabolic parameters / Int J Med Sci 13 : 124 ~ 132
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