개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.9
- 수록면
- 201 - 207 (7page)
이용수
초록· 키워드
오류제보하기
Measuring the pulse wave velocity (PWV) is a non-invasive method for evaluating the stiffness of the vessel wall. While previous studies investigated the association of uric acid level with arterial stiffness, most did not consider smoking status and obesity as covariates. The objective of this study was to investigate the relationship between uric acid levels and arterial stiffness, considering smoking status and obesity. We studied 3390 subjects (1940 males and 1450 females). Abnormal PWV was also defined as the highest quartile of values in the subjects. Data were analyzed using Pearson correlation, t-test, and multiple regression analysis. Approximately 41.9% of men and 3.7% of women were current smokers. Prevalence of hypertension was 11.4% in men and 7.0% in women. In women, hyperuricemia was associated with abnormal PWV (OR 1.58; 95% CI 1.03~2.43). Hyperuricemia was also associated with abnormal PWV (OR 2.37; 95% CI 1.01~5.59) in non- or light male smokers with normal blood pressure. This study suggests that uric acid is associated with arterial stiffness in women and non-smoking men.
목차
INTRODUCTION
SUBJECTS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (28)
참고문헌 신청
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Chen X, Li Y, Sheng CS, Huang QF, Zheng Y, Wang JG. Association of serum uric acid with aortic stiffness and pressure in a Chinese workplace setting. American Journal of Hypertension. 2010. 23: 387-392.
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Corry DB, Eslami P, Yamamoto K, Nyby MD, Makino H, Tuck ML. Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin-angiotensin system. Journal of Hypertension. 2008; 26: 269-275.
Czernichow S, Bertrais S, Oppert JM, Galan P, Blacher J, Ducimetiere P, Hercberg S, Zureik M. Body composition and fat repartition in relation to structure and function of large arteries in middle-aged adults (the SU.VI.MAX study). International Journal of Obesity. 2005. 29: 826-832.
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UCI(KEPA) : I410-ECN-0101-2018-510-001347482