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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 359 - 369 (11page)
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DNA methylation is emerging as an attractive marker providing investigative leads to solve crimes in forensic genetics. The identification of body fluids that utilizes tissue-specific DNA methylation can contribute to solving crimes by predicting activity related to the evidence material.
The age estimation based on DNA methylation is expected to reduce the number of potential suspects, when the DNA profile from the evidence does not match with any known person, including those stored in the forensic database.
Moreover, the variation in DNA implicates environmental exposure, such as cigarette smoking and alcohol consumption, thereby suggesting the possibility to be used as a marker for predicting the lifestyle of potential suspect. In this review, we describe recent advances in our understanding of DNA methylation variations and the utility of DNA methylation as a forensic marker for advanced investigative leads from evidence materials.
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참고문헌 (88)
참고문헌 신청
Kayser M / 2015 / Forensic DNA Phenotyping: Predicting human appearance from crime scene material for investigative purposes / Forensic Sci Int Genet 18:33~48
Santos F / 2013 / Forensic DNA databases in European countries: is size linked to performance? / Life Sci Soc Policy 9:12
European Network of Forensic Science Institutes DNA Working Group / Report on Criminal Cases in Europe solved by ILS (DNA Mass Testing)
Kayser M / 2009 / DNA-based prediction of human externally visible characteristics in forensics:motivations, scientific challenges, and ethical considerations / Forensic Sci Int Genet 3:154~161
Kayser M / 2011 / Improving human forensics through advances in genetics, genomics, molecular biology / Nat Rev Genet 12:179~192
Santos F / 2013 / Forensic DNA databases in European countries: is size linked to performance? / Life Sci Soc Policy 9:12
European Network of Forensic Science Institutes DNA Working Group / Report on Criminal Cases in Europe solved by ILS (DNA Mass Testing)
Kayser M / 2009 / DNA-based prediction of human externally visible characteristics in forensics:motivations, scientific challenges, and ethical considerations / Forensic Sci Int Genet 3:154~161
Kayser M / 2011 / Improving human forensics through advances in genetics, genomics, molecular biology / Nat Rev Genet 12:179~192
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