지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Cerebral small vessel disease (SVD), which includes white matter hyperintensities (WMHs), silent brain infarction (SBI), and cerebral microbleeds (CMBs), develops in a conjunction of cumulated injuries to cerebral microvascular beds, increased permeability of blood-brain barriers, and chronic oligemia. SVD is easily detected by routine neuroimaging modalities such as brain computed tomography or magnetic resonance imaging. Research has revealed that the presence of SVD markers may increase the risk of future vascular events as well as deteriorate functional recovery and neurocognitive trajectories after stroke, and such an association could also be applied to hemorrhagic stroke survivors. Currently, the specific mechanistic processes leading to the development and manifestation of SVD risk factors are unknown, and further studies with novel methodological tools are warranted. In this review, recent studies regarding the prognostic impact of WMHs, SBI, and CMBs on stroke survivors and briefly summarize the pathophysiological concepts underlying the manifestation of cerebral SVD.
목차
등록된 정보가 없습니다.
참고문헌 (70)
참고문헌 신청
이영배 / 2014 / Arterial Stiffness and Functional Outcome in Acute Ischemic Stroke / Journal of Cerebrovascular and Endovascular Neurosurgery 16(1):11~19
Carmichael ST / 2003 / Plasticity of cortical projections after stroke / Neuroscientist 9:64~75
Di Filippo M / 2008 / Plasticity and repair in the post-ischemic brain / Neuropharmacology 55:353~362
Wong TY / 2002 / Atheroslerosis Risk in Communities Study. Cerebral white matter lesions, retinopathy, and incident clinical stroke / JAMA 288:67~74
Vermeer SE / 2003 / Silent brain infarcts and white matter lesions increase stroke risk in the general population: the Rotterdam Scan Study / Stroke 34:1126~1129
Carmichael ST / 2003 / Plasticity of cortical projections after stroke / Neuroscientist 9:64~75
Di Filippo M / 2008 / Plasticity and repair in the post-ischemic brain / Neuropharmacology 55:353~362
Wong TY / 2002 / Atheroslerosis Risk in Communities Study. Cerebral white matter lesions, retinopathy, and incident clinical stroke / JAMA 288:67~74
Vermeer SE / 2003 / Silent brain infarcts and white matter lesions increase stroke risk in the general population: the Rotterdam Scan Study / Stroke 34:1126~1129
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