지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Background: Although the number of the elderly stroke patients increases, treatment with intravenous recombinant tissue plasminogen activator (rt-PA) is currently not recommended in the elderly. We investigated the safety and clinical outcome of the intravenous thrombolysis in the elderly. Methods: We consecutively enrolled patients who underwent intravenous rt-PA thrombolysis according to the treatment protocol based on the American heart association guidelines. The demographic data, initial national institutes of health stroke scale score and stroke subtype were assessed. The clinical outcomes were modified Rankin Scale (mRS) at 3 months. Symptomatic intracranial hemorrhage causing any neurological decline was evaluated. All clinical data were compared between patients who were 80 years or older and those less than 80 years. Results: Of the total 46 patients, 7 (15.2%) patients were 80 years or older. The baseline characteristics were comparable between both groups. Symptomatic hemorrhagic transformation was not different between both groups [0/7 (0%) vs. 3/39 (7.7%), P>0.999]. There was no difference in favorable outcome (mRS 0-2) and mortality between both groups [2/7 (28.6%) vs. 25/37 (67.6%), P=0.089, 1/7 (14.3%) vs. 4/37 (10.8%), P>0.999, respectively]. Conclusion: Symptomatic intracranial hemorrhage was not higher in the elderly and the favorable clinical outcome was comparable between the two groups. (Korean J Stroke 2010;12:102-105)
목차
등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
/ 1997 / Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. The NINDS t-PA Stroke Study Group / Stroke 28 : 2109 ~ 2118
Adams HP Jr / 1993 / Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatm
Adams HP Jr / 2007 / American Heart Association; American Stroke Association Stroke Council; Clinical Cardiology Council; Cardiovascular Radiology and Intervention Council; A
Berrouschot J / 2005 / Outcome and severe hemorrhagic complications of intravenous thrombolysis with tissue plasminogen activator in very old (>or=80 years) stroke patien
Chen CI / 2005 / Intravenous TPA for very old stroke patients / Eur Neurol 54 : 140 ~ 144
Adams HP Jr / 1993 / Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatm
Adams HP Jr / 2007 / American Heart Association; American Stroke Association Stroke Council; Clinical Cardiology Council; Cardiovascular Radiology and Intervention Council; A
Berrouschot J / 2005 / Outcome and severe hemorrhagic complications of intravenous thrombolysis with tissue plasminogen activator in very old (>or=80 years) stroke patien
Chen CI / 2005 / Intravenous TPA for very old stroke patients / Eur Neurol 54 : 140 ~ 144
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한국 뇌졸중 진료지침 급성기 치료 중 혈전용해술에 대한 내용의 부분개정
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Intravenous Recombinant Tissue Plasminogen Activator Thrombolysis in a Patient with Acute Ischemic Stroke Secondary to Aortic Dissection
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Magnetic Resonance Imaging in Acute Ischemic Stroke Treatment
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Simple Estimates of Symptomatic Intracranial Hemorrhage Risk and Outcome after Intravenous Thrombolysis Using Age and Stroke Severity
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A Novel Computerized Clinical Decision Support System for Treating Thrombolysis in Patients with Acute Ischemic Stroke
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Stroke: Morbidity, Risk Factors, and Care in Taiwan
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Repeated Thrombolytic Therapy in Patients with Recurrent Acute Ischemic Stroke
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정맥 혈전용해술과 관련된 뇌출혈에 대한 지혈치료 후 뇌경색이 악화된 증례
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Effectiveness and Safety of Thrombolysis in Ischemic Stroke Patients Aged 80 Years or Older
대한뇌졸중학회지
2012 .01
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80세 이상 급성기 허혈뇌졸중 환자에서 정맥내 혈전 용해 치료를 결정하는데 연관된 요인
대한뇌졸중학회지
2011 .01
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Tissue Plasminogen Activator 주입에 의한 뇌 경정맥동 혈전의 혈전용해에 관한 고찰
대한인터벤션영상기술학회지
1998 .05
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허혈성 뇌졸중과 두개내 대혈관질환에서 Plasminogen Activator Inhibitor의 유전자 다형성
대한뇌졸중학회지
2006 .01
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Cost-Effectiveness of Recombinant Tissue Plasminogen Activator in the Management of Acute Ischemic Stroke: A Systematic Review
Journal of Clinical Neurology
2010 .01
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Intravenous Thrombolysis in Patients with Acute Lacunar Infarction: Preliminary Study
대한뇌졸중학회지
2007 .01
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