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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 549 - 555 (7page)
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초록· 키워드
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Background/Aims: The aim of this study was to compare the clinical effects of preoperative and postoperative dexamethasone on pain after endoscopic submucosal dissection (ESD) for early gastric neoplasm. Methods: Forty patients with early gastric neoplasm who were scheduled for ESD were randomized into two groups according to the timing of steroid administration: preoperative (“pre”, n=20) and postoperative (“post”, n=20) steroid administration. The pre group received 0.15 mg/kg dexamethasone before ESD and placebo after, and the post group received pre-ESD placebo and post-ESD dexamethasone. The present pain intensity (PPI) index and the short-form McGill pain (SF-MP) questionnaire were evaluated. Results: The primary outcome was PPI score at 6 hours after ESD. There was a greater reduction in 6-hour PPI in the pre group than in the post group (2.1±0.8 vs 3.0±1.1, respectively; p=0.006). The immediate PPI was also significantly lower in the pre group than in the post group (1.6±0.6 vs 2.9±0.6, respectively; p<0.001), and the total SF-MP scores were significantly lower in the pre group than in the post group both immediately and at 6 hours after the operation. Conclusions: Preoperative administration of dexamethasone may produce a superior analgesic effect in patients who undergo ESD compared with the postoperative administration of dexamethasone.
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참고문헌 (28)
참고문헌 신청
Oka S / 2006 / Advantage of endoscopic submucosal dissection compared with EMR for early gastric cancer / Gastrointest Endosc 64:877~883
Kim B / 2015 / The efficacy of topical bupivacaine and triamcinolone acetonide injection in the relief of pain after endoscopic submucosal dissection for gastric neoplasia: a randomized double-blind, placebo-controlled trial / Surg Endosc 29:714~722
Lee H / 2012 / Clinical features and predictive factors of coagulation syndrome after endoscopic submucosal dissection for early gastric neoplasm / Gastric Cancer 15:83~90
Onogi F / 2010 / “Transmural air leak”: a computed tomographic finding following endoscopic submucosal dissection of gastric tumors / Endoscopy 42:441~447
Lee HW / 2014 / The efficacy of single-dose postoperative intravenous dexamethasone for pain relief after endoscopic submucosal dissection for gastric neoplasm / Surg Endosc 28:2334~2341
Kim B / 2015 / The efficacy of topical bupivacaine and triamcinolone acetonide injection in the relief of pain after endoscopic submucosal dissection for gastric neoplasia: a randomized double-blind, placebo-controlled trial / Surg Endosc 29:714~722
Lee H / 2012 / Clinical features and predictive factors of coagulation syndrome after endoscopic submucosal dissection for early gastric neoplasm / Gastric Cancer 15:83~90
Onogi F / 2010 / “Transmural air leak”: a computed tomographic finding following endoscopic submucosal dissection of gastric tumors / Endoscopy 42:441~447
Lee HW / 2014 / The efficacy of single-dose postoperative intravenous dexamethasone for pain relief after endoscopic submucosal dissection for gastric neoplasm / Surg Endosc 28:2334~2341
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