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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 168 - 175 (8page)
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초록· 키워드
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Background/Aims: Endoscopic treatment has been broadly applied to superficial esophageal neoplasms. Endoscopic submucosal dissection (ESD) allows for high rates of en bloc resection, precise histological assessment, and low rates of local recurrence. The aim of this study was to evaluate the outcomes of ESD for superficial esophageal neoplasms.
Methods: We retrospectively reviewed 36 esophageal ESDs for superficial squamous neoplasms in 32 patients between March 2009 and August 2014 at Gangnam Severance Hospital.
Results: The median patient age was 64 years, and 30 men were included. The indications were early squamous cell carcinoma in 26 lesions, adenoma with high-grade dysplasia in five lesions, and low-grade dysplasia in five lesions. The en bloc resection and R0 resection rates were 97.2% (35 of 36) and 91.7% (33 of 36), respectively. Microperforation and post-ESD bleeding occurred in 5.6% (2 of 36) and 5.6% (2 of 36), respectively. Post-ESD esophageal strictures developed in five patients (13.9%). Five patients (15.6%) had an additional treatment after ESD (concurrent chemoradiation therapy in three, radiation therapy in one, and surgery in one patient). There was no disease-specific mortality during the median follow-up of 31 months.
Conclusions: Favorable clinical outcomes were observed in ESD for superficial esophageal squamous neoplasms. Esophageal ESD could be a good treatment option in terms of efficacy and safety.
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등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Sano T / 1992 / Lymph node metastasis from early gastric cancer: endoscopic resection of tumour / Br J Surg 79:241~244
Oka S / 2006 / Endoscopic submucosal dissection for residual/local recurrence of early gastric cancer after endoscopic mucosal resection / Endoscopy 38:996~1000
Takahashi H / 2010 / Endoscopic submucosal dissection is superior to conventional endoscopic resection as a curative treatment for early squamous cell carcinoma of the esophagus (with video) / Gastrointest Endosc 72:255~264
Isomoto H / 2009 / Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study / Gut 58:331~336
Fujishiro M / 2008 / Perspective on the practical indications of endoscopic submucosal dissection of gastrointestinal neoplasms / World J Gastroenterol 14:4289~4295
Oka S / 2006 / Endoscopic submucosal dissection for residual/local recurrence of early gastric cancer after endoscopic mucosal resection / Endoscopy 38:996~1000
Takahashi H / 2010 / Endoscopic submucosal dissection is superior to conventional endoscopic resection as a curative treatment for early squamous cell carcinoma of the esophagus (with video) / Gastrointest Endosc 72:255~264
Isomoto H / 2009 / Endoscopic submucosal dissection for early gastric cancer: a large-scale feasibility study / Gut 58:331~336
Fujishiro M / 2008 / Perspective on the practical indications of endoscopic submucosal dissection of gastrointestinal neoplasms / World J Gastroenterol 14:4289~4295
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