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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 739 - 748 (10page)
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초록· 키워드
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Background/Aims: Endoscopic submucosal dissection (ESD) is an effective treatment for early gastric cancer (EGC) that has demonstrated a minimal risk of lymph node metastasis in retrospective studies. We sought to prospectively evaluate the short-term outcomes of ESD treatment in EGCs. Methods: A prospective multicenter cohort study of neoplasms 3 cm or less in diameter at endoscopic size evaluation was performed in 12 Korean ESD study grouprelated university hospitals and the National Cancer Center.
Resected specimens were evaluated by the central pathologic review board. Results: A patient cohort (n=712) with a total of 737 EGCs was analyzed. The margin-free en bloc resection rate was 97.3%, and curative resection of 640 lesions (86.8%) was achieved. Lower curative resection rates were associated with lesions 2 to 3 cm in size prior to ESD compared with lesions 2 cm or less in size (78.6% vs 88.1%, respectively, p=0.009). Significant factors associated with noncurative resection were moderately or poorly differentiated histological type, posterior wall tumor location, tumor size larger than 3 cm, ulceration, and submucosal invasion.
Delayed bleeding occurred in 49 patients (6.9%), and 12 patients (1.7%) exhibited perforations. Conclusions: ESD is an effective treatment with a high curative resection rate for EGCs that meets relatively conservative pre-ESD indications.
Long-term survival outcomes should be evaluated in followup studies.
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등록된 정보가 없습니다.
참고문헌 (42)
참고문헌 신청
서민아 / 2013 / Trends in Cancer Screening Rates among Korean Men and Women: Results from the Korean National Cancer Screening Survey, 2004-2012 / Cancer Research and Treatment 45(2):86~94
김윤경 / 2014 / Effects of Screening on Gastric Cancer Management: Comparative Analysis of the Results in 2006 and in 2011 / Journal of Gastric Cancer 14(2):129~134
Japanese Gastric Cancer Association / 2011 / Japanese gastric cancer treatment guidelines 2010 (ver. 3) / Gastric Cancer 14:113~123
Lian J / 2012 / A meta-analysis of endoscopic submucosal dissection and EMR for early gastric cancer / Gastrointest Endosc 76:763~770
Chung IK / 2009 / Therapeutic outcomes in 1000cases of endoscopic submucosal dissection for early gastric neoplasms:Korean ESD Study Group multicenter study / Gastrointest Endosc 69:1228~1235
김윤경 / 2014 / Effects of Screening on Gastric Cancer Management: Comparative Analysis of the Results in 2006 and in 2011 / Journal of Gastric Cancer 14(2):129~134
Japanese Gastric Cancer Association / 2011 / Japanese gastric cancer treatment guidelines 2010 (ver. 3) / Gastric Cancer 14:113~123
Lian J / 2012 / A meta-analysis of endoscopic submucosal dissection and EMR for early gastric cancer / Gastrointest Endosc 76:763~770
Chung IK / 2009 / Therapeutic outcomes in 1000cases of endoscopic submucosal dissection for early gastric neoplasms:Korean ESD Study Group multicenter study / Gastrointest Endosc 69:1228~1235
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