지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 27 - 37 (11page)
이용수
초록· 키워드
오류제보하기
Proton pump inhibitors (PPIs) were clinically introduced more than 25 years ago and have since proven to be invaluable, safe, and effective agents for the management of a variety of acid-related disorders. Although all members in this class act in a similar fashion, inhibiting active parietal cell acid secretion, there are slight differences among PPIs relating to their pharmacokinetic properties, metabolism, and Food and Drug Administration (FDA)-approved clinical indications. Nevertheless, each is effective in managing gastroesophageal reflux disease and uncomplicated or complicated peptic ulcer disease.
Despite their overall efficacy, PPIs do have some limitations related to their short plasma half-lives and requirement for meal-associated dosing, which can lead to breakthrough symptoms in some individuals, especially at night. Longeracting PPIs and technology to prolong conventional PPI activity have been developed to specifically address these limitations and may improve clinical outcomes.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Chiba N / 1997 / Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease:a meta-analysis / Gastroenterology 112 : 1798 ~ 1810
Eriksson S / 1995 / Omeprazole and H2-receptor antagonists in the acute treatment of duodenal ulcer, gastric ulcer and reflux oesophagitis: a metaanalysis / Eur J Gastroente
Esplugues JV / 2006 / Safety of proton pump inhibitors / Med Clin (Barc) 127 : 790 ~ 795
Farley A / 2000 / Rabeprazole versus ranitidine for the treatment of erosive gastroesophageal reflux disease:a double-blind, randomized clinical trial: Raberprazole Study Gro
Furuta T / 1998 / Effect of genetic differences in omeprazole metabolism on cure rates for Helicobacter pylori infection and peptic ulcer / Ann Intern Med 129 : 1027 ~ 1030
Eriksson S / 1995 / Omeprazole and H2-receptor antagonists in the acute treatment of duodenal ulcer, gastric ulcer and reflux oesophagitis: a metaanalysis / Eur J Gastroente
Esplugues JV / 2006 / Safety of proton pump inhibitors / Med Clin (Barc) 127 : 790 ~ 795
Farley A / 2000 / Rabeprazole versus ranitidine for the treatment of erosive gastroesophageal reflux disease:a double-blind, randomized clinical trial: Raberprazole Study Gro
Furuta T / 1998 / Effect of genetic differences in omeprazole metabolism on cure rates for Helicobacter pylori infection and peptic ulcer / Ann Intern Med 129 : 1027 ~ 1030
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