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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 65 - 70 (6page)
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초록· 키워드
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Cytomegalovirus (CMV) infection is one of the most common congenital infections. The first case of discordant congenital CMV infection in twins occurred in Korea. A 31-year-old woman became pregnant with twins (dichorionic-diamniotic). An elective caesarean section was performed at 37 weeks. The first baby was male, weighing 2,410 g with an Apgar score of 8/9. The second baby was female, weighing 1,380 g with an Apgar score of 5/8. She had experienced intrauterine growth retardation, and presented with microcephaly, micrognathia, and joint stiffness. During the work-up for discordant twins, the second baby's serum test was positive for CMV immunoglobulin M. Her urine, blood, and cerebrospinal fluid (CSF) were CMV polymerase chain reaction positive. The first baby's CMV tests were negative. Ophthalmologic exam and audiometry performed on the second baby showed CMV retinitis and bilateral sensorineural hearing loss. She was treated with intravenous ganciclovir. Currently, she is bed-ridden and has significant developmental delay. Although the causes of discordant congenital CMV infection in twins are unclear, this case shows that discordant congenital CMV infection should be considered in twins with significant differences in intrauterine growth or clinical symptoms after birth.
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등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Ahlfors K / 1988 / On the unpredictable development of congenital cytomegalovirus infection. A study in twins / Early Hum Dev 18 : 125 ~ 135
Azam AZ / 2001 / Prenatal diagnosis of congenital cytomegalovirus infection / Obstet Gynecol 97 : 443 ~ 448
Bodeus M / 1999 / Increased risk of cytomegalovirus transmission in utero during late gestation / Obstet Gynecol 93 (5 Pt 1) : 658 ~ 660
Egana-Ugrinovic G / 2016 / Congenital cytomegalovirus infection among twin pairs / J Matern Fetal Neonatal Med 29 : 3439 ~ 3444
Griesmaier E / 2010 / Neurodevelopmental outcome following congenital cytomegalovirus infection in preterm infants with twin-to-twin transfusion syndrome : a case report / K
Azam AZ / 2001 / Prenatal diagnosis of congenital cytomegalovirus infection / Obstet Gynecol 97 : 443 ~ 448
Bodeus M / 1999 / Increased risk of cytomegalovirus transmission in utero during late gestation / Obstet Gynecol 93 (5 Pt 1) : 658 ~ 660
Egana-Ugrinovic G / 2016 / Congenital cytomegalovirus infection among twin pairs / J Matern Fetal Neonatal Med 29 : 3439 ~ 3444
Griesmaier E / 2010 / Neurodevelopmental outcome following congenital cytomegalovirus infection in preterm infants with twin-to-twin transfusion syndrome : a case report / K
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