지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Dioscorea japonica Thunberg (DJ) has been widely used as a healthy food in Korea for the enhancement of physical stamina. Hence, the present study evaluated the immune-enhancing effect of DJ in forced swim test of mouse model. The immobility time of the group treated with DJ for 7 days was significantly reduced in comparison with that of the control group. After a forced swimming test, the changes in blood biochemical parameters and splenic T lymphocyte populations induced by the administration of DJ were assessed. Serum levels of lactic dehydrogenase, creatine phosphokinase, and aspartate aminotransferase were significantly decreased in DJ-administered group compared to the control group. However, administration of DJ did not affect the splenic T lymphocyte populations. Moreover, DJ significantly increased the production of interferon-g and interleukin-2 compared to the media control in splenocytes. Collectively, it may be concluded that DJ is useful for enhancement of physical and immune function.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Conclusion
References
참고문헌 (33)
참고문헌 신청
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Connor TJ, Kelly JP, Leonard BE. Forced swim test-induced neurochemical endocrine, and immune changes in the rat. Pharmacol. Biochem. Behav. 58: 961-967 (1997)
Costill DL, Fink WJ. Plasma volume changes following exercise and thermal dehydration. J. Appl. Physiol. 37: 521-525 (1974)
Delbende C, Tranchand Bunel D, Tarozzo G, Grino M, Oliver C, Mocaer E, Vaudry H. Effect of chronic treatment with the antidepressant tianeptine on the hypothalamo-pituitary-adrenal axis. Eur. J. Pharmacol. 251: 245-251 (1994)
Cohn L, Ray A. T-helper type 2 cell-directed therapy for asthma. Pharmacol. Ther. 88: 187-196 (2000)
Connor TJ, Kelly JP, Leonard BE. Forced swim test-induced neurochemical endocrine, and immune changes in the rat. Pharmacol. Biochem. Behav. 58: 961-967 (1997)
Costill DL, Fink WJ. Plasma volume changes following exercise and thermal dehydration. J. Appl. Physiol. 37: 521-525 (1974)
Delbende C, Tranchand Bunel D, Tarozzo G, Grino M, Oliver C, Mocaer E, Vaudry H. Effect of chronic treatment with the antidepressant tianeptine on the hypothalamo-pituitary-adrenal axis. Eur. J. Pharmacol. 251: 245-251 (1994)
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