지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.5
- 수록면
- 49 - 55 (7page)
이용수
초록· 키워드
오류제보하기
A variety of commercially processed ginseng products, including black snow ginseng (BSG), sun ginseng (SG), and red ginseng (RG) are currently available in the market. To evaluate the anti-wrinkle effects of Panax ginseng (BSG, SG, and RG) water extracts (PGWEs: BSGWE, SGWE, and RGWE), collagen synthesis and degradation abilities of PGWEs were assessed using human dermal fibroblasts. BSGWE, SGWE, and RGWE at the concentration of 50 ㎍/mL increased type-I procollagen synthesis by 82.7% (p＜0.001), 26.9% (p＜0.01), and 119.2% (p＜0.001), respectively, in comparison to control cells. In comparison to control cells, treatments with 50 ㎍/mL of BSGWE, SGWE, and RGWE significantly (p＜0.001) decreased the activity of matrix metalloproteinase-2 (MMP-2) and the mRNA and protein expression of MMP-1. PGWEs were found to promote collagen synthesis and inhibit its degradation in human dermal fibroblasts. Among PGWEs, RGWE showed the most effective anti-wrinkle effects.
목차
Abstract
Introduction
Materials and Methods
Results
Discussion
References
참고문헌 (32)
참고문헌 신청
[학술지(정기간행물)] - Lupo MP / 2005 / Cosmeceutical peptides / Dermatol Surg 31 : 832 ~ 836
[학술지(정기간행물)] - Fisher GJ / 2002 / Mechanisms of photoaging and chronological skin aging / Arch Dermatol 138 : 1462 ~ 1470
[학술지(정기간행물)] - Dhalla AK / 1996 / Role of oxidative stress in transition of hypertrophy to heart failure / J Am Coll Cardiol 28 : 506 ~ 514
[학술지(정기간행물)] - Fisher GJ / 1997 / Pathophysiology of premature skin aging induced by ultraviolet light / N Engl J Med 337 : 1419 ~ 1428
[학술지(정기간행물)] - Brennan M / 2003 / Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin / Photochem Photobiol 78 : 43 ~ 48
[학술지(정기간행물)] - Fisher GJ / 2002 / Mechanisms of photoaging and chronological skin aging / Arch Dermatol 138 : 1462 ~ 1470
[학술지(정기간행물)] - Dhalla AK / 1996 / Role of oxidative stress in transition of hypertrophy to heart failure / J Am Coll Cardiol 28 : 506 ~ 514
[학술지(정기간행물)] - Fisher GJ / 1997 / Pathophysiology of premature skin aging induced by ultraviolet light / N Engl J Med 337 : 1419 ~ 1428
[학술지(정기간행물)] - Brennan M / 2003 / Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin / Photochem Photobiol 78 : 43 ~ 48
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UCI(KEPA) : I410-ECN-0101-2018-047-002155024