지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Totally, one hundred and sixty 1-day-old Ross 308 broiler chicks were fed with a diet containing 0, 0.5, 1.0, and 2.0 mg of aflatoxin B1(AFB1)/kg of feed for 21 days. Body weight was lower for the AFB1-treated broilers than for the control group. At 14 and 21 DPF, the broilers fed with 2.0 mg of AFB1/kg of feed weighed significantly lower than those of the other groups (p<0.05). Relative liver weights increased significantly in a dose-dependent manner, and relative spleen weights were significantly high in the chicks fed with 2.0 mg of AFB1/kg of feed at 21 DPF (p<0.001). Biochemical analyses showed that total protein and albumin levels decreased significantly at 7 and 14 DPF for the chicks of the group fed with 2.0 of mg AFB1/kg of feed, compared with those fed with 0.5 and 1.0 mg of AFB1/kg of feed (p<0.05). AST and ALT levels increased significantly at 14 and 21 DPF (p<0.05), and the AST levels, particularly, increased dose-dependently (p<0.05). Histopathological analyses showed that the liver tissues of the AFB1-treated chicks showed significant lesions, including hemorrhage, hepatocyte necrosis, inflammatory cell infiltration, and fatty degeneration. The severity of both hepatocyte necrosis and inflammatory cell infiltration appeared to increase dose- and time-dependently. Similarly, hepatic fibrosis increased dosedependently (p<0.05). The results of this study could improve our understanding of parameters used for evaluating aflatoxicosis in poultry.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (23)
참고문헌 신청
[학술지(정기간행물)] - Chen X / 2014 / Efficiency of hydrated sodium calcium aluminosilicate to ameliorate the adverse effects of graded levels of aflatoxin B1 in broiler chicks / Poult Sci 93 : 2037 ~ 2047
[학술지(정기간행물)] - Diaz GJ / 2008 / Aflatoxicosis in chickens (Gallus gallus): An example of hormesis? / Poult Sci 87 : 727 ~ 732
[학술지(정기간행물)] - Fowler J / 2015 / Effects of a calcium bentonite clay in diets containing aflatoxin when measuring liver residues of aflatoxin B1 in starter broiler chicks / Toxins (Basel) 7 : 3455 ~ 3464
[학술지(정기간행물)] - Huff WE / 1986 / Progression of aflatoxicosis in broiler chickens / Poult Sci 65 : 1891 ~ 1899
[학술지(정기간행물)] - Hussain Z / 2016 / Determination of liver and muscle aflatoxin B1 residues and select serum chemistry variables during chronic aflatoxicosis in broiler chickens / Vet Clin Pathol 45 : 330 ~ 334
[학술지(정기간행물)] - Diaz GJ / 2008 / Aflatoxicosis in chickens (Gallus gallus): An example of hormesis? / Poult Sci 87 : 727 ~ 732
[학술지(정기간행물)] - Fowler J / 2015 / Effects of a calcium bentonite clay in diets containing aflatoxin when measuring liver residues of aflatoxin B1 in starter broiler chicks / Toxins (Basel) 7 : 3455 ~ 3464
[학술지(정기간행물)] - Huff WE / 1986 / Progression of aflatoxicosis in broiler chickens / Poult Sci 65 : 1891 ~ 1899
[학술지(정기간행물)] - Hussain Z / 2016 / Determination of liver and muscle aflatoxin B1 residues and select serum chemistry variables during chronic aflatoxicosis in broiler chickens / Vet Clin Pathol 45 : 330 ~ 334
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UCI(KEPA) : I410-ECN-0101-2018-527-001730415