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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.22 No.2
- 발행연도
- 2017.6
- 수록면
- 100 - 106 (7page)
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초록· 키워드
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To elucidate new biological ingredients in cold-brew coffee extracted with cold water, crude polysaccharide (CCP-0) was isolated by ethanol precipitation, and its immune-stimulating activities were assayed. CCP-0 mainly comprised galactose (53.6%), mannose (15.7%), arabinose (11.9%), and uronic acid (12.4%), suggesting that it might exist as a mixture of galactomannan and arabinogalactan. CCP-0 significantly increased cell proliferation on both murine peritoneal macrophages and splenocytes in a dose dependent manner. CCP-0 also significantly augmented nitric oxide and reactive oxygen species production by murine peritoneal macrophages. In addition, macrophages stimulated by CCP-0 enhanced production of various cytokines such as tumor necrosis factor-α, interleukin (IL)-6, and IL-12. In an in vitro assay for intestinal immune-modulating activity, CCP-0 showed higher bone-marrow cell-proliferation activity through Peyer’s patch cells at 100 μg/mL than the negative control. These results suggest that CCP-0 may potentially enhance macrophage functions and the intestinal immune system.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (32)
참고문헌 신청
[학술지(정기간행물)] - Higdon JV / 2006 / Coffee and health : a review of recent human research / Crit Rev Food Sci Nutr 46 : 101 ~ 123
[학술지(정기간행물)] - Kim AR / 2014 / Flavor contributing nonvolatile chemical and sensory characterization of cold water extractionbased coffee by different extraction methods(dripping vs steeping)and time / Journal of The Korea Society for Coffee Industry 3 : 1 ~ 9
[학술지(정기간행물)] - Oh YA / 2014 / A study on anti-bacterial activity of cold-brewed coffee extracts / Journal of The Korea Society for Coffee Industry 3 : 26 ~ 33
[학술지(정기간행물)] - Panchal SK / 2012 / Coffee extract attenuates changes in cardiovascular and hepatic structure and function without decreasing obesity in highcarbohydrate, high-fat diet-fed male rats / J Nutr 142 : 690 ~ 697
[학술지(정기간행물)] - Yukawa GS / 2004 / Effects of coffee consumption on oxidative susceptibility of low-density lipoproteins and serum lipid levels in humans / Biochemistry 69 : 70 ~ 74
[학술지(정기간행물)] - Kim AR / 2014 / Flavor contributing nonvolatile chemical and sensory characterization of cold water extractionbased coffee by different extraction methods(dripping vs steeping)and time / Journal of The Korea Society for Coffee Industry 3 : 1 ~ 9
[학술지(정기간행물)] - Oh YA / 2014 / A study on anti-bacterial activity of cold-brewed coffee extracts / Journal of The Korea Society for Coffee Industry 3 : 26 ~ 33
[학술지(정기간행물)] - Panchal SK / 2012 / Coffee extract attenuates changes in cardiovascular and hepatic structure and function without decreasing obesity in highcarbohydrate, high-fat diet-fed male rats / J Nutr 142 : 690 ~ 697
[학술지(정기간행물)] - Yukawa GS / 2004 / Effects of coffee consumption on oxidative susceptibility of low-density lipoproteins and serum lipid levels in humans / Biochemistry 69 : 70 ~ 74
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