지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.12
- 수록면
- 326 - 329 (4page)
이용수
초록· 키워드
오류제보하기
Deoxyribonucleotides (dNTPs) are important for the efficient growth of DNA viruses. Therefore, many DNA viruses have strategies for the upregulation of cellular dNTP levels. Both α- and γ-herpesviruses encode functional homologs of cellular dNTP anabolic enzymes, including the class I ribonucleotide reductase (RNR) large (R1) and small (R2) subunits, whereas β-herpesviruses modulate host cells to induce genes that increase dNTP levels. Interestingly, β-herpesviruses still express the nonfunctional RNR R1 subunit. However, it is not clear why β-herpesviruses still carry inactive R1 homologs. Recently, the R1 homologs of herpesviruses have been shown to inhibit innate immune signaling pathways. In particular, both functional and nonfunctional R1 homologs target receptor-interacting protein kinase 1 (RIP1) and inhibit RIP1-mediated signaling pathways to promote viral replication. Here, we summarize recent findings on the activity of herpesviral R1 homologs and discuss their roles in the regulation of innate immune signaling pathways.
목차
INTRODUCTION
CLOSING REMARKS
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
B Cell Infection by Kaposi’s Sarcoma-associated Herpesvirus
한국미생물학회 학술대회논문집
2016 .04
-
Rim11, the Human GSK-3β Homolog Is Involved in Replication Stress Response in Yeasts
한국미생물학회 학술대회논문집
2016 .04
-
Beyond Viral Interferon Regulatory Factors: Immune Evasion Strategies
Journal of Microbiology and Biotechnology
2019 .01
-
Comparison of Growth Kinetics of Equine Herpesvirus 1 in NBL-6, RK-13, MDBK, Vero, HeLa Cell Lines
한국미생물학회 학술대회논문집
2022 .10
-
Viral Inhibition of PRR-Mediated Innate Immune Response: Learning from KSHV Evasion Strategies
Molecules and Cells
2016 .11
-
Regulatory Mechanisms of Ribonucleotide Reductases in the DNA Replication Stress in Cryptococcus neoformans
한국미생물학회 학술대회논문집
2021 .08
-
Advantage sensitivity in enzyme linked aptamer assay with DNA homolog of the RNA tetracycline aptamer
한국분석과학회 학술대회
2017 .11
-
Susceptibility of KSHV-Infected PEL Cell Lines to the Human Complement System
Journal of Microbiology and Biotechnology
2016 .01
-
Dynamics of Viral and Host 3D Genome Structure upon Infection
Journal of Microbiology and Biotechnology
2022 .12
-
The Roles of Pds5, One of Cohesin-modulator Factors, in Meiotic Recombination, Homolog Pairing and Axis Formation
한국미생물학회 학술대회논문집
2020 .10
-
Mitochondrial Targeting Domain Homologs Induce Necrotic Cell Death Via Mitochondrial and Endoplasmic Reticulum Disruption
Journal of Microbiology and Biotechnology
2021 .01
-
Modulation of the IFN-β and NF-κB Signaling Pathways by Chikungunya Virus-encoded Genes
한국미생물학회 학술대회논문집
2020 .10
-
Identification and Functional Analysis of RelA/SpoT Homolog (RSH) Genes in Deinococcus radiodurans
Journal of Microbiology and Biotechnology
2016 .12
-
Isolation and Molecular Characterization of Feline Herpesvirus 1 from Naturally Infected Korean Cats
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2020 .12
-
Role of HCMV Tegument Proteins in Receptor-Interacting Protein Kinase 1 (RIP1)-Mediated NF-κB Signaling
한국미생물학회 학술대회논문집
2015 .04
-
Pathogenesis of Oncoviruses: A Systemic Review
한국미생물·생명공학회지
2023 .06
-
Alterations in Acetylation of Histone H4 Lysine 8 and Trimethylation of Lysine 20 Associated with Lytic Gene Promoters during Kaposi’s Sarcoma-Associated Herpesvirus Reactivation
Journal of Microbiology and Biotechnology
2017 .01
-
Exonuclease I and Cohesin Rec8 Promote Establishment of Homolog Interaction in Meiotic Recombination of Budding Yeast
한국미생물학회 학술대회논문집
2020 .10
-
Genome‑wide mining of respiratory burst homologs and its expression in response to biotic and abiotic stresses in Triticum aestivum
Genes & Genomics
2019 .01
-
Chemical Genetics Approach Reveals Importance of cAMP and MAP Kinase Signaling to Lipid and Carotenoid Biosynthesis in Microalgae
Journal of Microbiology and Biotechnology
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2017-475-002003614