지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이 논문의 연구 히스토리 (8)
2019
Rapid determination and quantification of hair-growth compounds in adulterated products by ultra HPLC coupled to quadrupole-orbitrap MS
Ji Hyun Lee
,
Han Na Pa
,
k
외 6명
분석과학
2019.04
학술저널
Detection of phenobarbital adulteration in dietary supplements : simultaneous analysis of 16 sedative-hypnotics and sleep-inducers by ultra-high-performance liquid chromatography with UV detection (UPLC-UV) and quadruple Orbitrap mass spectrometry (Q-Orbitrap-MS)
Ji Hyun Lee
,
Ji Yeon Choi
,
Hanna Pa
외 8명
분석과학
2019.02
학술저널
2016
Analysis of erectile dysfunction drugs and their analogues in counterfeit drugs and herbal medicines by LC-ESI-MS/MS : Supplementary data
Ji Hyun Lee
,
Ji Hye Jeong
,
Hyoung-Joon Pa
외 5명
분석과학
2016.08
학술저널
Analysis of erectile dysfunction drugs and their analogues in counterfeit drugs and herbal medicines by LC-ESI-MS/MS
Ji Hyun Lee
,
Ji Hye Jeong
,
Hyoung-Joon Pa
외 5명
분석과학
2016.08
학술저널
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Distribution of various illegal or counterfeit drugs of seven approved erectile dysfunction drugs and their analogues has been increased, causing health problems such as cardiovascular disorder, tachycardia, headache, or vision disturbance. We used liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) to determine the erectile dysfunction drugs and their analogues in various counterfeit drugs. Eleven erectile dysfunction drugs and their analogues were detected, with sildenafil and its analogues being the most counterfeited compounds (73.8 %), followed by tadalafil and its analogues (25.4 %). The limits of detection (LOD) and the limits of quantitation (LOQ) of liquid-type and solid-type negative samples ranged from 0.1 to 3.3 ng/mL or ng/g and from 0.3 to 10.0 ng/mL or ng/g, respectively. The recoveries ranged from 84.3 to 112.3 % and 83.2 to 110.2 %, respectively. The contents of sildenafil and tadalafil in the various counterfeit drugs ranged from 21.0 to 947.5 mg/g and from 0.2 to 170.2 mg/g, respectively.
목차
Abstract
1. Introduction
2. Experimental
3. Results and Discussion
4. Conclusion
References
참고문헌 (12)
참고문헌 신청
[학술지(정기간행물)] - M. Alp / 2013 / / J. Pharm. Biomed. Anal 72 : 155 ~ 158
[학술지(정기간행물)] - Y. H. Lam / 2008 / / J. Pharm. Biomed. Anal 46 : 804 ~ 807
[학술지(정기간행물)] - C. -L. Kee / 2012 / / J. Pharm. Biomed. Anal 70 : 265 ~ 272
[학술지(정기간행물)] - E. S. Lee / 2013 / / J. Pharm. Biomed. Anal 83 : 171 ~ 178
[학술지(정기간행물)] - P. Zou / 2006 / / J. Chromatogr. A 1104 : 113 ~ 122
[학술지(정기간행물)] - Y. H. Lam / 2008 / / J. Pharm. Biomed. Anal 46 : 804 ~ 807
[학술지(정기간행물)] - C. -L. Kee / 2012 / / J. Pharm. Biomed. Anal 70 : 265 ~ 272
[학술지(정기간행물)] - E. S. Lee / 2013 / / J. Pharm. Biomed. Anal 83 : 171 ~ 178
[학술지(정기간행물)] - P. Zou / 2006 / / J. Chromatogr. A 1104 : 113 ~ 122
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Analysis of erectile dysfunction drugs and their analogues in counterfeit drugs and herbal medicines by LC-ESI-MS/MS : Supplementary data
분석과학
2016 .08
-
Rapid screening and confirmation of erectile dysfunction drug and its analogues by ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry
한국분석과학회 학술대회
2015 .05
-
Utilization of LC-MS/MS in Drug Development
한국분석과학회 학술대회
2024 .11
-
Development of analytical methods for the detection of stanozolol in counterfeit drugs
한국분석과학회 학술대회
2016 .11
-
Rapid screening of erectile dysfunction drugs in dietary supplements based on the double CID UHPLC-Q/TOF-MS
한국분석과학회 학술대회
2015 .11
-
High-throughput Drug Interaction Study using LC-MS/MS
한국분석과학회 학술대회
2015 .11
-
Next Generation Sequencing and Bioinformatics
생명과학회지
2015 .03
-
Determination of methamphetamine and amphetamine enantiomers in human urine by chiral stationary phase liquid chromatography-tandem mass spectrometry
분석과학
2019 .10
-
Monitoring of anti-impotence drug, anti-obesity drugs and their analogues in foods
한국분석과학회 학술대회
2016 .05
-
Determination of streptomycin in kiwifruit samples using LC-ESI-MS/MS
분석과학
2015 .08
-
LC-MS/MS Method for Simultaneous Analysis of Growth Hormone-Releasing Peptides and Secretagogues in Human Urine
Mass Spectrometry Letters
2016 .09
-
Forensic analysis for identification of counterfeit functional health water
한국분석과학회 학술대회
2019 .05
-
Quality management strategies for drug development
한국분석과학회 학술대회
2016 .11
-
Strategies to Isolate Drug-resistant Strains and to Identify New Drug Resistance Mechanisms
한국미생물학회 학술대회논문집
2022 .10
-
Erratum to “Analysis of potential drug-drug interactions in the intensive care unit using healthcare claims database and drug information database”
한국데이터정보과학회지
2019 .01
-
LC-MS/MS를 이용한 베타락탐계 항생제와 베타차단제의 동시분석
분석과학
2016 .08
-
Simultaneous analysis and monitoring of preservatives in drugs and quasi drugs
한국분석과학회 학술대회
2016 .05
-
Analysis method development of anti-obesity drugs in health functional foods by LC/PDA and LC/MS
한국분석과학회 학술대회
2015 .05
-
LC-MS/MS 시스템을 이용한 모유 중 파라벤류 분석법 확립
대한화학회지
2016 .04
-
Screening and identification of PDE-5 inhibitors and counterfeit drugs in supplements by GC-MS/MS-dynamic MRM combined with trimethylsilylation
한국분석과학회 학술대회
2018 .05
이 논문의 저자 정보
이 논문과 함께 이용한 논문
Development and validation of an LC-MS/MS method for the simultaneous analysis of 26 anti-diabetic drugs in adulterated dietary supplements and its application to a forensic sample
Nam Sook Kim
,
Geum Joo Yoo
,
Kyu Yeon Kim
외 5명
분석과학
2019
.04
High-throughput Drug Interaction Study using LC-MS/MS
Kwang-Hyeon Liu
,
Jeongmin Joo
,
Bo
외 2명
한국분석과학회 학술대회
2015
.11
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2017-433-001146394