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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.21 No.1
- 발행연도
- 2016.3
- 수록면
- 9 - 13 (5page)
이용수
초록· 키워드
오류제보하기
The present study was conducted to investigate the effects of beverages containing fermented Akebia quinata extracts on alcoholic hangover. For this study, 25 healthy young men were recruited. All participants consumed 100 mL of water (placebo), commercial hangover beverage A or B, fermented A. quinata leaf (AQL) or fruit (AQF) extract before alcohol consumption. After 1 h, all participants consumed a bottle of Soju, Korean distilled liquor (360 mL), containing 20% alcohol. Blood was collected at 0 h, 1 h, 3 h, and 5 h after alcohol consumption. The plasma alanine transaminase (ALT) activity was highest in the placebo group. Compared with the control group, the AQL and AQF groups showed decreased ALT activity at 5 h after alcohol consumption. Plasma ethanol concentration was increased after alcohol intake and peaked at 3 h after alcohol consumption. Compared with the control group, the A group showed a higher plasma ethanol concentration at 1 h (P＜0.05). At 3 h after alcohol consumption, the AQF group showed the lowest mean plasma ethanol concentration compared to the other groups; however, there were no statistical differences. After 5 h of alcohol consumption, the AQL and AQF groups showed lower plasma ethanol concentrations compared with the B group. The sensory evaluation score for the fermented A. quinata fruit extract was lower than for the commercial hangover beverages. In conclusion, the present intervention study results suggest that fermented A. quinata extracts alleviate alcoholic hangover and reduce plasma ethanol concentrations.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (24)
참고문헌 신청
An SW, Kim YG, Kim MH, Lee BI, Lee SH, Kwon HI, Hwang B, Lee HY. 1999. Comparison of hepatic detoxification activity and reducing serum alcohol concentration of Hovenia dulcis THUNB and Alnus Japonica Steud. Korean J Med Crop Sci 7: 263- 268.
Rehm J, Mathers C, Popova S, Thavorncharoensap M, Teerawattananon Y, Patra J. 2009. Global burden of disease and injury and economic cost attributable to alcohol use and alcohol- use disorders. Lancet 373: 2223-2233.
Swift R, Davidson D. 1998. Alcohol hangover: mechanisms and mediators. Alcohol Health Res World 22: 54-60.
Kim KW, Yang JS, Lee JS, Cho YS, Kang SK, Chung HK. 1994. Activity of alcohol dehydrogenase and ethanol, acetaldehyde levels in normal adult blood. Korean Ind Hyg Assoc J 4: 240-247.
Helander A, Tottmar O. 1988. Effect of acute ethanol administration on human blood aldehyde dehydrogenase activity. Alcohol Clin Exp Res 12: 643-646.
Rehm J, Mathers C, Popova S, Thavorncharoensap M, Teerawattananon Y, Patra J. 2009. Global burden of disease and injury and economic cost attributable to alcohol use and alcohol- use disorders. Lancet 373: 2223-2233.
Swift R, Davidson D. 1998. Alcohol hangover: mechanisms and mediators. Alcohol Health Res World 22: 54-60.
Kim KW, Yang JS, Lee JS, Cho YS, Kang SK, Chung HK. 1994. Activity of alcohol dehydrogenase and ethanol, acetaldehyde levels in normal adult blood. Korean Ind Hyg Assoc J 4: 240-247.
Helander A, Tottmar O. 1988. Effect of acute ethanol administration on human blood aldehyde dehydrogenase activity. Alcohol Clin Exp Res 12: 643-646.
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UCI(KEPA) : I410-ECN-0101-2016-594-002777680