지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.12
- 수록면
- 171 - 177 (7page)
이용수
초록· 키워드
오류제보하기
Bifidobacteria is one of the prototypes of probiotics bacteria, normally inhabitating the intestinal tract of humans. To search for a potent immunoregulatory Bifidobacteria strain, we screened the Bifidobacteria strains isolated from the feces of healthy Korean children. The mRNA or protein expression of an anti-inflammatory cytokine, IL-10, from mouse macrophages stimulated with live Bifidobacteria was examined. Of tested strains, Bifidobacteria A28 induced the highest IL-10 gene expression of murine macrophages. To probe immunoregulatory activity of the selected strain on the mice, we evaluated the proportional changes of CD4?CD25? surface marker in the murine splenocytes. Flow cytometric analysis showed that the overall percentages of CD4?CD25? cells in A28-treated splenocytes were higher than those of untreated splenocytes. In parallel, IL-10 release from A28-treated mouse peritoneal macrophages and splenocytes was significantly higher than that of untreated control cells. Collectively, the Bifidobacteria A28 strain isolated from the feces of healthy Korean children augments the mRNA or protein expression of IL-10 release from mouse peritoneal macrophages as well as the proportion of CD4?CD25? cells of naive splenocytes. These provide in vitro scientific clues that Bifidobacteria A28 might be usable for anti-inflammatory disease such as inflammatory bowel disease (IBD).
목차
서론
재료 및 방법
결과
고찰
참고문헌
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
CD43 Expression Regulated by IL-12 Signaling Is Associated with Survival of CD8 T Cells
Immune Network
2010 .10
-
Role for CD40 and CD40L Expression in Generating CD8 T Cell Response to Minor Histcompatibility Antigen, H60
Immune Network
2007 .12
-
Cross-linking of CD80 and CD86 Diminishes Expression of CD54 on EBV-transformed B Cells through Inactivation of RhoA and Ras
Immune Network
2011 .12
-
CD40L 발현 K562 세포주를 이용한 시험관내 B 세포 증식과 항원제공능 증가
Immune Network
2007 .06
-
Two Distinct Subsets Are Identified from the Peritoneal Myeloid Mononuclear Cells Expressing both CD11c and CD115
Immune Network
2019 .06
-
Extrinsic Acquisition of CD80 by Antigen-Specific CD8⁺ T Cells Regulates Their Recall Immune Responses to Acute Viral Infection
Immune Network
2019 .08
-
杏仁 분획물이 Th2 cytokine 발현과 NC/Nga mouse의아토피 피부염에 미치는 영향
대한한방소아과학회지
2016 .01
-
Requirement of CD4 Help for Induction of CD8 T Cell Response Specific for Virally Derived H60
Immune Network
2012 .06
-
Regulation of Inflammation by Bidirectional Signaling through CD137 and Its Ligand
Immune Network
2012 .10
-
간세포암에서 CD40 과 CD154의 발현
Annals of Hepato-Biliary-Pancreatic Surgery
2007 .12
-
CD137-CD137 Ligand Interactions in Inflammation
Immune Network
2009 .06
-
비소세포 폐암종의 CD44s 와 Cycylooxygenase-2 발현
Journal of Pathology and Translational Medicine
2006 .01
-
Adhesion of CD40-stimulated Germinal Center B Cells to HK Cells Employs the CD11a/CD18-CD54 Interactions
Immune Network
2003 .09
-
Significance of Expression of CD44s and CD44v6 in Colorectal Cancer
대한의생명과학회지
2002 .09
-
Effect of IL-4 on the Development and Function of Memory-like CD8 T Cells in the Peripheral Lymphoid Tissues
Immune Network
2016 .04
-
Expression and Function of TLR2 on CD4 Versus CD8 T Cells
Immune Network
2009 .08
-
Recombinant TAT-CD137 Ligand Cytoplasmic Domain Fusion Protein Induces the Production of IL-6 and TNF-α in Peritoneal Macrophages
Immune Network
2011 .08
-
비소세포폐암종에서 CD44s, CD44v5 및 CD44v6 발현의 임상병리학적 의의
Journal of Pathology and Translational Medicine
2004 .01
-
조절 T세포에 미치는 梔子의 효과
대한한방내과학회지
2010 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0