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Korean hemorrhagic fever(KHF) reported for the first time in Korea in 1951,although in had previously been knowin both Manchuria and Russia. After the Korean War, the disease was designated as endemic in the area of the Demilitarized Zone, and since then from 100 to 800cases have been reported every year. The outbreak of patients had been localized in the vicinity of the DMZ until 1970 but since 1971 the disease has invaded the southern areas of the Korean peninsula. Lee et al"' ' reported the isolation of KHF virus from the patients and Apodemus agrarius collected in the endemic areas and developed diagnosis method for serological of KHF recently In the present report, SGOT,SGPTand LDH levels of 9 KHF patients during the course of illness were studied and obtained following results. Six cases out of 9KHF patients showed increased levels of SGOT and SGPT after 2-4 weeks from onset of fever. LDH values of the sera of KHF patients were incresaed 1 week before the increase of transaminase and then decreased slowly during the course of hemorrhagic fever.

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UCI(KEPA) : I410-ECN-0101-2016-475-001514836