이번 연구는 일개 사업장 근로자를 대상으로 24시간 활동혈압에 따른 고혈압군과 정상군의 불안과 우울정도를 비교하고 불안증상과 우울증상에 따른 혈압 양상을 비교 분석하고자 하였다. 일개 사업장 근로자 107명을 대상으로 2009년 12월 10일부터 2010년 3월 20일까지 사업장을 방문하여 BAI와 BDI로 불안과 우울정도를 조사하였고 임상혈압과 24시간 AMBP로 활동혈압을 측정하였다. 임상혈압과 24시간 AMBP에서 고혈압군과 정상군의 BAI와 BDI 점수는 모두 유의한 차이가 없었지만, 우울증상군에서 정상군보다 야간 이완기혈압 비강하 발생위험도가 6.85배 (CI 1.50-30.01)높았다. 고혈압 치료를 시작하거나 치료 중인 환자에서 치료순응율을 향상시키고 심혈관계 질환 예방을 위해서는 심리적인 중재도 필요하다고 판단되어진다.
Objectives: Anxiety and depression are known to be associated with hypertension, and blood pressure can vary spontaneously throughout the day. The aim of this study was to evaluate anxiety, depression and 24-hour ambulatory blood pressure (24-h ambulatory BP) in employees at their worksite. Methods: A total of 107 volunteers among 136 employees at a hotel in Gyeongju, Korea were enrolled in this study between December 2009 and March 2010. The Beck Anxiety Inventory (BAI) and the Beck Depression Inventory (BDI) were used to assess anxiety and depression, respectively. Blood pressure was measured using a 24-h ambulatory BP monitoring system. Results: No significant differences in either BAI or BDI scores were found when hypertensive individuals were compared to normotensive individuals. The frequency of diastolic non-dipper was significantly higher in individuals with depressive symptoms compared to those without (p<0.05). Depression was significantly associated with diastolic non-dipper (OR: 6.85, 95% CI: 1.50-30.01). Conclusions: The results of this study indicate that depression should be considered when deciding upon blood pressure control regimens, and appropriate additive psychotherapy may be beneficial in the treatment of hypertensive patients.