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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2009.4
- 수록면
- 552 - 555 (4page)
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This study investigated the proapoptotic effect of ethanol extracts obtained from dandelion (Taraxacum officinale) flower on human ovarian cancer SK-OV-3 cells. Cells were treated with dandelion flowers ethanol extract (DFE) ranging from 1.5625 to 100 ㎍/㎖ for 24 hr. Significant antiproliferative effects of DFE were first observed from at 6.25 ㎍/㎖ (p＜0.05), and this inhibition showed in a dose-dependent manner. When cells were treated with more than 6.25 ㎍/㎖ DFE, cell-cycle analysis showed that DFE caused an increase in the percentage of sub-G0/G1 cells and arrested at the S and G2/M phase in a dose-dependent manner. Moreover, apoptosis induction by DFE involved p53 activation and bax upregulation as well as downregulation of bcl-2. Our findings indicate that DFE resulted in apoptotic cell death, suggesting that DFE possesses potential anticancer properties.
목차
Abstract
Introduction
Materials and Methods
Results and Discussion
Acknowledgments
References
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Protective Effect of Dandelion Extracts on Ethanol-Induced Acute Hepatotoxicity in C57BL/6 Mice
Journal of Food Science and Nutrition
2008 .12
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[P10-83] Nutritional Analysis and Antioxidative Activity from Dandelion (Taraxacum officinale) Kimchi
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민들레의 영양성분에 관한 연구
Food Science and Preservation
1999 .12
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[OP-05] Mechanism of Cell Cycle Arrest and Apoptosis in Human Ovarian Cancer SK-OV-3 Cells during Serum Restriction
한국식품영양과학회 학술대회발표집
2006 .10
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민들레(Taraxacum officinale) 잎과 뿌리의 페놀산 조성 및 활성산소 소거활성
Food Science and Preservation
2008 .06
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[P8-323] Hepatoprotective Effects of Dandelion (Taraxacum officinale) Ethanol Extracts against 2, 3, 7, 8-Tetrachlorodibenzo-ρ-dioxin (TCDD)-induced Toxicities
한국식품영양과학회 학술대회발표집
2009 .11
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Biological Properties of Different Types and Parts of the Dandelions : Comparisons of Anti - Oxidative, Immune Cell Proliferative and Tumor Cell Growth Inhibitory Activities
Journal of Food Science and Nutrition
2005 .06
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당 첨가 민들레(Taraxacum officinale) 발효 추출물의 발효과정 중 이화학적 및 미생물학적 변화
Food Science and Preservation
2012 .02
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[P8-279] Ethanol Induced-Hepatoprotective Effects of Taraxacum officinale in vivo
한국식품영양과학회 학술대회발표집
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민들레 물추출물의 항산화 및 자유라디칼 소거활성
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2002 .06
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A5E promotes Cell growth Arrest and Apoptosis in Non Small Cell Lung Cancer
Journal of applied biological chemistry
2014 .01
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Antioxidant and hepatoprotective effect of fermented Taraxacum officinale extracts
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2015 .08
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Induction of ROS-Mediated Cell Cycle Arrest and Apoptosis by Ethanol Extract of Inula japonica Flowers in HT-1080 Human Fibrosarcoma Cells
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Comparison of Nutritional Components and Antioxidative Activity of Taraxacum coreanum and Taraxacum officinale
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2015 .08
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국화과 추출물의 암세포 증식 억제 효과
한국식품영양과학회지
2012 .05
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The Anti-Obesity Effect of Extract of Dandelion (Taraxacum Platycarpum) Containing High Luteolin Supplementation in High-Fat Diet-Induced Obese Mice
한국식품영양과학회 학술대회발표집
2016 .10
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Antimicrobial Effects of Extracts of Taraxacum officinale H. on Acnes Strains
한국식품영양과학회 학술대회발표집
2011 .10
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UCI(KEPA) : I410-ECN-0101-2013-573-000856252