지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.12
- 수록면
- 355 - 362 (8page)
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초록· 키워드
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In this study, the anticoagulant compounds in Korean red ginseng (KRG) were investigated. KRG powder was extracted using hot methanol, and the methanol extract was fractionated into n-hexane, ethylacetate, n-butanol, and aqueous fractions by solvent partitioning. The remains from the methanol extraction were further extracted with water and then dialyzed to obtain low and high molecular weight fractions. The anticoagulant activities of the seven fractions were evaluated in terms of thrombin time, prothrombin time, and activated partial thromboplastin time. Among these fractions, the ethylacetate fraction showed the most potent anticoagulant activity. The active components in the ethylacetate fraction were identified as the phenolic compounds vanillic, caffeic, ferulic, and p-coumaric acid via TLC and HPLC. These findings suggest that the anticoagulant activities of phenolic compounds contribute to the cardiovascular effects of KRG.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (25)
참고문헌 신청
1. [학술지(정기간행물)] - Han KH / 1998 / Effect of red ginseng on blood pressure in patients with essential hypertension and white coat hypertension / Am J Chin Med 26 : 199 ~ 209
2. [학술지(정기간행물)] - Sung J / 2000 / Effects of red ginseng upon vascular endothelial function in patients with essential hypertension / Am J Chin Med 28 : 205 ~ 216
3. [학술대회논문] - Hirai A / 1999 / Studies on the mechanisms of anti-platelet and anti-atherosclerotic effects of the Korean red ginseng: focusing on arachidonic acid cascade / Proceedings of ‘99 Korea-Japan Ginseng Symposium : 16 ~ 31
4. [학술지(정기간행물)] - 윤여표 / 2007 / 건강한 지원자에서 홍삼농축액의 혈행 개선효과: 무작위, 이중맹검, 위약-대조 시험 / Journal of Ginseng Research 31 (2) : 109 ~ 116
5. [학술지(정기간행물)] - Lee JH / 1995 / The effect of the long-term ginseng intakes on serum lipids profile and hemostatic factors in human / Korean J Nutr 28 : 862 ~ 871
2. [학술지(정기간행물)] - Sung J / 2000 / Effects of red ginseng upon vascular endothelial function in patients with essential hypertension / Am J Chin Med 28 : 205 ~ 216
3. [학술대회논문] - Hirai A / 1999 / Studies on the mechanisms of anti-platelet and anti-atherosclerotic effects of the Korean red ginseng: focusing on arachidonic acid cascade / Proceedings of ‘99 Korea-Japan Ginseng Symposium : 16 ~ 31
4. [학술지(정기간행물)] - 윤여표 / 2007 / 건강한 지원자에서 홍삼농축액의 혈행 개선효과: 무작위, 이중맹검, 위약-대조 시험 / Journal of Ginseng Research 31 (2) : 109 ~ 116
5. [학술지(정기간행물)] - Lee JH / 1995 / The effect of the long-term ginseng intakes on serum lipids profile and hemostatic factors in human / Korean J Nutr 28 : 862 ~ 871
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UCI(KEPA) : I410-ECN-0101-2012-524-004168281