Assessment of the Optimum LDL : HDL-cholesterol(LDL : HDL-C) Ratio for Predicting CHD

Yeoum Soon Gyo

Assessment of the Optimum LDL : HDL-cholesterol(LDL : HDL-C) Ratio for Predicting CHD

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심혈관질환 예측을 위한 저밀도 대 고밀도 지단백 콜레스테롤 비(LDL : HDL-cholesterol ratio)의 적정기준에 관한 연구

Type: Academic journal

Author: Yeoum Soon Gyo (서일대학)

Journal: Korean Society of Adult Nursing Korean Journal of Adult Nursing Vol.20 No.6 KCI Candidated Journals SCOPUS

Published: 2008.12

Pages: 917 - 931 (15page)

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Assessment of the Optimum LDL : HDL-cholesterol(LDL : HDL-C) Ratio for Predicting CHD

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Purpose: This study was aimed to determine the optimum low-density lipoprotein : high-density lipoprotein-cholesterol (LDL : HDL-C) ratio for predicting coronary heart disease(CHD) in Korean people. Methods: It was analyzed this data of 5,431 adults who had undergone health examinations in a hospital in Gyeonggi-do between January 2006 and December 2007. The covariation of the coronary risk factors such as age, HbA1C, systolic blood pressure(SBP), and waist-to-stature ratio(WSR) were analyzed by using logistic regression analysis. Results: The LDL : HDL-C ratio in the male and female groups was mostly distributed between 1.5 and 4.0. The LDL : HDL-C ratio was the most significant cholesterol-related parameter influencing CHD (male: B = .306, p = .054, female : B = .940, p = .010), followed by LDL-C and total cholesterol. It was observed a sharp increase in the odds ratios for LDL : HDL-C ratios of 2.25 - 2.50(male) and 2.00 - 2.25(female). A significant difference was observed in both male(2.25 : x² = 2.494, p = .072) and female(2.00 : x² = 413.742, p = .000) groups. Conclusion: The risk level of CHD was set to 2.25 for males and 2.00 for females. Therefore, the optimum LDL : HDL-C ratio for Koreans should be far lower than that for the people in western countries.

#Coronary heart disease #LDL #HDL #Cholesterol

Ⅰ. 서론
Ⅱ. 연구방법
Ⅲ. 연구결과
Ⅳ. 논의
Ⅴ. 결론 및 제언
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1. [학술지(정기간행물)] - Choi, S. Y / 2005 / A study on the correlation among total serum cholesterol level, blood pressure, body mass index and lifestyle / J Korean Acad Nurs 17 (1) : 149 ~ 159

2. [단행본] - Department of Internal Medicine, Seoul National Medical School / 2005 / Update in internal medicine / Korea Medical Co.

3. [학술지(정기간행물)] - Expert panel on detection and treatment of high blood cholesterol in adults / 2001 / Executive summary of the third report of the national cholesterol education program(NCEP)(Adult treatment panel 3) / J Am Med Assoc 285 (19) : 2486 ~ 2497

4. [학술지(정기간행물)] - Evans, A / 2001 / Trends in coronary risk factors in the WHO MONICA Project / Inter Epidemiol Assoc 30 : S35 ~ S40

5. [학술지(정기간행물)] - Ha, H. Y / 1997 / Correlation between obesity indics and cardiovascular risk factors and usefullness of abdominal obesity indics / Korean J Prev Med 30 (2) : 327 ~ 341

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Fields Medicine and Pharmacy > Nursing Science Interdisciplinary Studies > Interdisciplinary Research

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UCI(KEPA) : I410-ECN-0101-2012-512-003972489

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