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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.12
- 수록면
- 561 - 564 (4page)
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This study was performed to investigate the proper method for evaluating normal hepatic function in healthy miniature pigs. Six male miniature pigs were divided into 3 groups. After general anesthesia, the phytate group and the BrIDA group had hepatoscintigraphy using 5 mCi of <SUP>99m</SUP>Tc-phytate and 99mTcbromotrimethyl IDA (BrIDA), respectively. And the Tc-O₄? group had per rectal portal scintigraphy (PRPS) using 10 mCi of 99mTc-pertechnetate (O₄?). In our study, <SUP>99m</SUP>Tc-phytate hepatoscintigraphy revealed lung uptake of phytate. However, it was better to observe liver than hepatoscintigraphy using <SUP>99m</SUP>Tc-tin colloid in our previous study. <SUP>99m</SUP>Tc-BrIDA hepatoscintigraphy showed good liver image to examine the hepatic function. And it was easy and fast for imaging compared to hepatoscintigraphy using <SUP>99m</SUP>Tc-phytate. However, <SUP>99m</SUP>Tc-O₄? PRPS showed poor result to examine the hepatic function. It only showed radioactivity in rectum and did not show it in liver and other organs. <SUP>99m</SUP>Tc-BrIDA hepatoscintigraphy was the best diagnostic method to evaluate the hepatic function in miniature pigs. However, SPECT and radiopharmaceuticals for SPECT are disappearing and PET is used mainly in Korea. Therefore, new evaluating method of hepatic function using PET in miniature pigs will be needed.
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감사의 글
참고문헌
참고문헌 (16)
참고문헌 신청
1. [학술지(정기간행물)] - Dondelinger, R.F. / 1998 / Relevant radiological anatomy of the pig as a training model in interventional radiology / Eur. Radiol 8 (7) : 1254 ~ 1273
2. [학술지(정기간행물)] - Ibrahim, Z. / 2006 / Selected physiologic compatibilities and incompatibilities between human and porcine organ systems / Xenotransplantation 13 (6) : 488 ~ 499
3. [학술지(정기간행물)] - Jeong, S.Y. / 2003 / Evaluation of liver function using 99mTc-lactosylated serum albumin liver scintigraphy in rat with acute hepatic injury induced by dimethylnitrosamine / Korean J. Nucl. Med 37 : 418 ~ 427
4. [학술지(정기간행물)] - Kim, K.W. / 1989 / Evaluation of portal circulation in liver diseases by per - rectal portal scintigraphy / Kor. J. Gastroenterol 21 (4) : 857 ~ 868
5. [학술지(정기간행물)] - 김세은 / 2007 / 건강한 미니돼지에서 간담도 기능의 핵의학적 평가 / 한국임상수의학회지 24 (4) : 593 ~ 596
2. [학술지(정기간행물)] - Ibrahim, Z. / 2006 / Selected physiologic compatibilities and incompatibilities between human and porcine organ systems / Xenotransplantation 13 (6) : 488 ~ 499
3. [학술지(정기간행물)] - Jeong, S.Y. / 2003 / Evaluation of liver function using 99mTc-lactosylated serum albumin liver scintigraphy in rat with acute hepatic injury induced by dimethylnitrosamine / Korean J. Nucl. Med 37 : 418 ~ 427
4. [학술지(정기간행물)] - Kim, K.W. / 1989 / Evaluation of portal circulation in liver diseases by per - rectal portal scintigraphy / Kor. J. Gastroenterol 21 (4) : 857 ~ 868
5. [학술지(정기간행물)] - 김세은 / 2007 / 건강한 미니돼지에서 간담도 기능의 핵의학적 평가 / 한국임상수의학회지 24 (4) : 593 ~ 596
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UCI(KEPA) : I410-ECN-0101-2009-510-015707055