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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.3
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- 1 - 7 (7page)
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Organ transplantation is limited by the shortage of human organs. Many studies have sought to overcome this hurdle by using animal organs. Porcine organs, especially from miniature pigs, have been used for organ xenotransplantation rather than nonhuman primates. While the molecular profiling for transplantation is well known in humans and rodents, the situation for pigs is almost completely unknown. The present study examined protein regulation of the developing stages of the pancreatic proteome (4 day-old miniature neonate, 19 day-old miniature piglet, and 14 month-old miniature adult pigs) using twodimensional gel electrophoresis and matrix assisted laser desorption/ionization-time of flight mass spectrometry. Thirteen different expressed spots were observed and nine were identified. The data presented within this study provides critical direction relating to the development of pancreas of miniature pigs, which will assist future proteome analysis of the pancreas, and advance our understanding of the hurdles facing xenotransplantation.
목차
Materials and Methods
Results
Discussion
References
참고문헌 (34)
참고문헌 신청
1. [학술지(정기간행물)] - Cooper DK. / 2002 / Will the pig solve the transplantation backlog? / Annu Rev Med 53 : 133 ~ 147
2. [학술지(정기간행물)] - Platt JL. / 2000 / Physiologic barriers to xenotransplantation / Transplant Proc 32 (7) : 1547 ~ 1548
3. [학술지(정기간행물)] - Jung Min Ryu / 2009 / Imaging evaluation of the liver using multi-detector row computed tomography in micropigs as potential living liver donors / Journal of Veterinary Science 10 (2) : 93 ~ 98
4. [학술지(정기간행물)] - Ibrahim Z. / 2006 / Selected physiologic compatibilities and incompatibilities between human and porcine organ systems / Xenotransplantation 13 (6) : 488 ~ 499
5. [학술지(정기간행물)] - Tucker A. / 2002 / The production of transgenic pigs for potential use in clinical xenotransplantation : baseline clinical pathology and organ size studies / Xenotransplantation 9 (3) : 203 ~ 208
2. [학술지(정기간행물)] - Platt JL. / 2000 / Physiologic barriers to xenotransplantation / Transplant Proc 32 (7) : 1547 ~ 1548
3. [학술지(정기간행물)] - Jung Min Ryu / 2009 / Imaging evaluation of the liver using multi-detector row computed tomography in micropigs as potential living liver donors / Journal of Veterinary Science 10 (2) : 93 ~ 98
4. [학술지(정기간행물)] - Ibrahim Z. / 2006 / Selected physiologic compatibilities and incompatibilities between human and porcine organ systems / Xenotransplantation 13 (6) : 488 ~ 499
5. [학술지(정기간행물)] - Tucker A. / 2002 / The production of transgenic pigs for potential use in clinical xenotransplantation : baseline clinical pathology and organ size studies / Xenotransplantation 9 (3) : 203 ~ 208
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UCI(KEPA) : I410-ECN-0101-2015-500-001364407