지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 1999.12
- 수록면
- 145 - 153 (9page)
이용수
초록· 키워드
오류제보하기
OBJECTIVES : Author tried to evaluate the hypnotic effect of melatonin and melatonin induced daytime sleepiness and to identify the cumulative effect of short-term administration of melatonin for 3 successive days, and remaining effect after discontinuation.
INTERVENTION : Subjects visited our laboratory by 08:00 at the first day, and they had baseline MSLT(from 10:00 to 22:00 at 2 hours' interval) while they had 7 naps during the day. Each time, the Subjects completed SSS and RT before they underwent an MSLT to evaluate their sleepiness and to evaluate their performance. Next day, 6㎎ of melatonin was administered to healthy young males at 09:00 hour, and the concurrent effects on sleep latency, daytime sleepiness and reaction time were recorded.
PARTICIPANTS : Sixteen healthy, normal young male college students participated in this study. Participating subjects were in good physical and psychological health and were asymptomatic as to sleep/wake complaints
RESULT : The result were summarized as follows.
1. As compared to baseline, the hypnotic effect of melatonin appeared within 1 hour, and the effect continued over 7 hours. Sleep latency was normal range on the day of discontinuation.
2. Subjects had significantly more subjective daytime sleepiness after melatonin administration. Melatonin induced daytime sleepiness appeared within 3 hour after adminisration, and the condition continued over 7 hours.
3. Compared to baselines, there was no effect on reaction time.
4. The longer the reaction time of second drug administration day, the longer the reaction time of third drug administration day.
INTERVENTION : Subjects visited our laboratory by 08:00 at the first day, and they had baseline MSLT(from 10:00 to 22:00 at 2 hours' interval) while they had 7 naps during the day. Each time, the Subjects completed SSS and RT before they underwent an MSLT to evaluate their sleepiness and to evaluate their performance. Next day, 6㎎ of melatonin was administered to healthy young males at 09:00 hour, and the concurrent effects on sleep latency, daytime sleepiness and reaction time were recorded.
PARTICIPANTS : Sixteen healthy, normal young male college students participated in this study. Participating subjects were in good physical and psychological health and were asymptomatic as to sleep/wake complaints
RESULT : The result were summarized as follows.
1. As compared to baseline, the hypnotic effect of melatonin appeared within 1 hour, and the effect continued over 7 hours. Sleep latency was normal range on the day of discontinuation.
2. Subjects had significantly more subjective daytime sleepiness after melatonin administration. Melatonin induced daytime sleepiness appeared within 3 hour after adminisration, and the condition continued over 7 hours.
3. Compared to baselines, there was no effect on reaction time.
4. The longer the reaction time of second drug administration day, the longer the reaction time of third drug administration day.
목차
영어 초록
서론
연구대상 및 방법
연구성적
고찰
결론
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UCI(KEPA) : I410-ECN-0101-2009-513-017206236