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자료유형
학술저널
저자정보
저널정보
대한생물치료정신의학회 생물치료정신의학 생물치료정신의학 제9권 제1호
발행연도
2003.6
수록면
69 - 79 (11page)

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Objectives : The purpose of this study was to evaluate the effect of alcohol on sedation and some cognitive function(eg, daytime sleepiness, fatigue, and mood measured by multiple sleep latency test(MSLT) and visual analogue scale(VAS), vigilance, attention and short-term memory measured by Vienna Test System).
Methods : 15 healthy, normal young college students participated in this study. Participating subjects were in good physical and psychological health and were asymptomatic as to sleep/wake complaints. Subjects visited our laboratory by 08 : 00 at the first day, and they had baseline MSLT and Test(at 9 ; 00, 11 ; 00, 14 : 00, and 16 : 00). Each time, the subjects completed VAS for sleepiness, fatigue and mood before they underwent an Vienna Test to evaluate their Vigilance, attention and short-term memory. On the second day, subjects had 0.5g/㎏ of alcohol, the third day, subjects had 1.0g/㎏ of alcohol, and repeated the same process as those of the first.
Results : 0.5g/㎏ of alcohol reduced sleep latency after 1 hour, and 1.0g/㎏ of alcohol reduced sleep latency until 5 hours after administration significantly. 0.5g/㎏ of alcohol induced daytime sleepiness 1 hour after administration, and 1.0g/㎏ of alcohol induced daytime sleepiness and fatigue until 3 hours after administration, but there were no effects on mood. Vigilance was decreased significantly 1 hour after 0.5g/㎏ of alcohol administration, and attention and short-term memory were not changed significantly after alcohol administration. After alcohol administration (0.5-1.0g/㎏), there were significant positive correlation between daytime sleepiness and fatigue, and fatigue and mood.
Conclusion : It can be concluded that alcohol decreases sleep latency and induces daytime sleepiness and fatigue, and decreases vigilance in normal subjects.

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