지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.11 No.1
- 발행연도
- 2006.3
- 수록면
- 84 - 87 (4page)
이용수
초록· 키워드
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Antioxidant activity of Akebia quinata Decne was evaluated. Water extract (0.5 g/ 50 mL) of flowers and leaves of A. quinata were prepared and total phenol contents and radical scavenging activity of the extracts was determined for antioxidant activity. The total phenol contents of extracts from A. quinata flowers (FAQ) and leaves (LAQ) were 30.05 μM and 20.23 μM, while the radical scavenging activity of FAQ and LAQ were 60.51% and 52.97%, respectively. In addition, the effect of FAQ and LAQ extract on DNA damage induced by H₂O₂ in human lymphocytes was evaluated by comet assay. The FAQ and LAQ showed strong inhibitory effect against DNA damage induced by 200 μM of H₂O₂. These results suggest that water extracts of A. quinata Decne flowers and leaves showed significant (p＜0.05) antioxidant activity and protective effect against oxidative DNA damage.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
CONCLUSION
ACKNOWLEDGEMENT
REFERENCES
참고문헌 (27)
참고문헌 신청
Oh SD, Doo HK, Cho DH, Ahn SY. 1994. Effects of Akebia quinata Decne and Stephania tetrandra S. Moore on rats with acute renal failure induced by gentamicin sulfate. K H Med 10: 13-25.
Yook CS, Cha SM. 1989. Studies on the constituents of Akebia quinata var Polyphylla. Bull K H Pharma Sci 17: 69-74.
Choi J, Jung HJ, Lee KT, Park HJ. 2005. Antinociceptive and anti-inflammatory effects of the saponin and sapogenins obtained from the stem of Akebia quinata. J Med Food 8: 78-85.
Jung HJ, Lee CO, Lee KT, Park HJ. 2004. Structureactivity relationship of oleanane disaccharides isolated from Akebia quinata versus cytotoxicity against cancer cells and NO inhibition. Biol Pharm Bull 27: 744-747.
Buxiang S, Fukuhara M. 1997. Effects of co-administration of butylated hydroxytoluene, butylated hydroxyanisole and flavonoide on the activation of mutagens and drug-metabolizing enzymes in mice. Toxicology 122: 61-72.
Yook CS, Cha SM. 1989. Studies on the constituents of Akebia quinata var Polyphylla. Bull K H Pharma Sci 17: 69-74.
Choi J, Jung HJ, Lee KT, Park HJ. 2005. Antinociceptive and anti-inflammatory effects of the saponin and sapogenins obtained from the stem of Akebia quinata. J Med Food 8: 78-85.
Jung HJ, Lee CO, Lee KT, Park HJ. 2004. Structureactivity relationship of oleanane disaccharides isolated from Akebia quinata versus cytotoxicity against cancer cells and NO inhibition. Biol Pharm Bull 27: 744-747.
Buxiang S, Fukuhara M. 1997. Effects of co-administration of butylated hydroxytoluene, butylated hydroxyanisole and flavonoide on the activation of mutagens and drug-metabolizing enzymes in mice. Toxicology 122: 61-72.
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