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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Journal of Food Science and Nutrition Journal of Food Science and Nutrition Vol.10 No.1
- 발행연도
- 2005.3
- 수록면
- 34 - 39 (6page)
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초록· 키워드
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This study examined the anti-diabetic effect of a silkworm extract in C57BL/6J mice, an ob/db model, fed a high fat diet for 8 weeks. The body weight was not significantly different with the silkworm-extract supplement, nor did food intake and body weight gains also did not differ significantly among the high-fat diet groups. However, the water intake by the silkworm-extract supplemented groups increased significantly compared with that by the distilled-water supplement group, nonetheless, the FER did not differ significantly. For all groups, the blood glucose increased the most after 30 minutes and yet returned to a fasting level within 90 minutes. The fasting time and resulting glucose tolerance for the silkworm-extract supplemented groups were significantly decreased compared to that for the high fat diet with distilled water supplement group, while the level of blood glucose in silkworm-extract supplemented groups was significantly decreased compared with than in the diabetic control group. The HbA1c and insulin levels were no different among the groups. The sucrase and lactase activities in the proximal small intestine were significantly decreased in the silkworm-extract supplement groups compared to that in the diabetic control group. There was no significant difference in the glycogen contents in the liver and muscle among the groups. In conclusion, it was found that the silkworm-extract supplement repressed the disaccharidase activity in the small intestines mucosa of the C57BL/6J mice.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
ACKNOWLEDGEMENTS
REFERENCES
참고문헌 (32)
참고문헌 신청
FNB (Food and Nutrition Board). 1974. Recommended dietary all owanles national academy of science.
Goodhart RB, Shills ME. 1976. Modern nutrition in health and disease. Lea and Febiger, Philadelphia. p 900-901.
Hutton B, Fergusson D. 2004. Changes in body weight and serum lipid profile in pbese patients treated with orlistat in addition to hypocaloric diet: a systematic review of randomized-clinical trials. Am J Clin Nutr 80: 1461- 1468.
Nakatani K, Noma K, Nishioka J, Kasai Y, Morioka K, Katsuki A, Hori Y, Yano Y, Sumida Y, Wada H, Nobori T. 2005. Adiponectin gene variation associates with the increasing risk of type 2 diabetes in non-diabetic Japanese subjects. Int J Mol Med 15: 173-137
Skidmore PM, Yarnell JW. 2004. The obesity epidemic: prospects for prevention. QJM 97: 817-825.
Goodhart RB, Shills ME. 1976. Modern nutrition in health and disease. Lea and Febiger, Philadelphia. p 900-901.
Hutton B, Fergusson D. 2004. Changes in body weight and serum lipid profile in pbese patients treated with orlistat in addition to hypocaloric diet: a systematic review of randomized-clinical trials. Am J Clin Nutr 80: 1461- 1468.
Nakatani K, Noma K, Nishioka J, Kasai Y, Morioka K, Katsuki A, Hori Y, Yano Y, Sumida Y, Wada H, Nobori T. 2005. Adiponectin gene variation associates with the increasing risk of type 2 diabetes in non-diabetic Japanese subjects. Int J Mol Med 15: 173-137
Skidmore PM, Yarnell JW. 2004. The obesity epidemic: prospects for prevention. QJM 97: 817-825.
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