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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2001.3
- 수록면
- 9 - 13 (5page)
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초록· 키워드
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Essential hypertension is considered to be a multifactorial disease that is influenced not only by environmental factors but also by genetic factors. Genes involved in lipoprotein synthesis, modification and metabolism are candidates for essential hypertension. The purpose of this study was to estimate gene frequencies of paraoxonase/arylesterase (PON1) gene in Korean population and investigate the relationship between genotypes of this gene and essential hypertension or cardiovascular risk factors. In order to estimate the genotype frequencies, Alw I RFLP of PON1 gene was used as genetic marker. There were no significant differences in allele and genotype frequencies between normotensives and essential hypertensives, respectively. However, Alw I RFLP of PON1 gene were significantly associated with plasma HDL-cholesterol level in Korean population (oneway ANOVA test, P = 0.008). Therefore, our result suggest that this RFLP of PON1 gene may be protective marker on cardiovascular disease in Korean population.
목차
ABSTRACT
Introduction
Materials and Methods
Results
Discussion
Acknowledgments
References
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Association between Genetic Variation in the Human Factor Ⅶ Gene and Essential Hypertension in Korean Population
한국환경성돌연변이·발암원학회지
2001 .09
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Association of Paraoxonase-1(Q192R and L55M) Gene Polymorphisms and Activity with Colorectal Cancer and Effect of Surgical Intervention
Asian Pacific journal of cancer prevention : APJCP
2015 .01
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다환성 방향족 탄화수소 노출에 의한 DNA 산화적 손상과 paraoxonase-1 (PON1) 유전자 다형성이 폐암 발생에 미치는 영향
예방의학회지
2005 .01
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Two Genetic Polymorphisms of the Human Lupoprotein Lupase Gene in Korean Patients with Essential Hypertension
한국환경성돌연변이·발암원학회지
2002 .03
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Paraoxonase 1 (PON1) Q192R Gene Polymorphism and Cancer Risk: A Meta-Analysis Based on 30 Publications
Asian Pacific journal of cancer prevention : APJCP
2015 .01
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Association between Genetic Variation in the Human Antithrombin Ⅲ Gene and Essential Hypertension in Korean Population
한국환경성돌연변이·발암원학회지
2002 .03
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A Bal I RFLP of Dopamine D3 Receptor Gene in Korean Hypertensives
한국환경성돌연변이·발암원학회지
2003 .03
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Association Study between the Genetic Variations of the Apo AⅠ-CⅢ-AⅣ Gene Cluster and Hypertension among Koreans
Toxicological Research
2002 .12
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DNA Polymorphisms of the Human CYP11B2 and γ Subunit of ENaC Genes in Korean Hypertensives
한국환경성돌연변이·발암원학회지
2002 .12
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한국인 본태성 고혈압군에서 에스트로젠 수용체-α 유전자에 존재하는 다형성의 분포에 관한 연구
Environmental Analysis Health and Toxicology
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Association between Arg16Gly Mutation in the β₂-Adrenergic Receptor Gene and Hypertension in the Korean Population
한국환경성돌연변이·발암원학회지
2001 .09
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한국인 집단에서 심방 나트륨 이뇨 펩티드 유전자에 존재하는 유전적 변이와 본태성 고혈압과의 관련성에 관한 연구
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Genetic Epidemiology of Renin-Angiotensin System in Korean Population
한국환경성돌연변이·발암원학회지
2002 .03
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Linkage Disequilibrium of Dopamine D2 Receptor Gene in the Korean Population
Toxicological Research
2004 .03
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The Case-Control Studies Between The Single Nucleotide Polymorphisms of the Human SA and MTHFR Gene and Hypertension in Korean Popluation
한국환경성돌연변이·발암원학회지
2002 .09
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폐암발생의 위험인자로서 흡연과 Paraoxonase 1 유전자 다형성
Tuberculosis and Respiratory Diseases
2005 .01
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Haplotype Distribution of the β₂-Adrenergic Receptor Gene in Korean Essential Hypertensives
Toxicological Research
2002 .09
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Association of ATP6AP2 Gene Polymorphisms with Essential Hypertension in a south Chinese Han Population
Asian Pacific journal of cancer prevention : APJCP
2015 .01
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SNP Analysis of the Human LDL Receptor and CETP Gene in Korean Subjects with Hypertension
한국환경성돌연변이·발암원학회지
2002 .03
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UCI(KEPA) : I410-ECN-0101-2009-476-013746853