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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2002.9
- 수록면
- 233 - 240 (8page)
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초록· 키워드
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In view of the effect of β₂-adrenergic receptors (β₂-AR) as a risk factor for essential hypertension, we investigated the Fnu4HI and MnlI RFLPs of β₂-AR gene in the Korean patients with essential hypertension and normal controls. There were no significant differences in the allele and genotype of these polymorphism between normotensive and essential hypertensive subjects. In ethnic comparison, the allele frequencies of these three sites contained Nde I RFLP, reported the association with essential hypertension in Korean population previously, were very different from those of other ethnic populations studied. The significant linkage disequilibrium was detected only in hypertensive group between Nae I and Fnu4HI sites. The Fnu4HI RFLP was also significantly association between Fnu4HI variation in the human β₂-AR gene and plasma TG level may reflect the potential role of human β₂-AR gene as one of the genetic components for cardiovascular risk.
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UCI(KEPA) : I410-ECN-0101-2009-513-013456469