지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2001.9
- 수록면
- 95 - 98 (4page)
이용수
초록· 키워드
오류제보하기
β₂-adrenergic receptors (β₂-AR) contribute to cardiovascular regulation by influencing several functions and a several studies suggest that a decreased function of the β₂-AR may be involved in essential hypertension. We investigated the Arg16Gly mutation of β₂-AR gene, which show enhanced agonist-promoted downregulation of the receptor and yielded different results in terms of association with essential hypertension. We studied the relationship between genetic variation in the b2-adrenergic receptor gene and hypertension in a Korean population using Nde I restriction fragment length polymorphism (RFLP) analysis. There were significant differences in allele and genotype frequencies between essential hypertensive and normotensive group (Odds ratio(CI) = 1.71 (1.09-2.70)). Therefore, our result suggests that the Nde I RFLP of the β₂-adrenergic receptor gene may be useful as a genetic marker in hypertension diagnostics in Korean population.
목차
ABSTRACT
Introduction
Materials and Methods
Results
Discussion
Acknowledgement
References
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Haplotype Distribution of the β₂-Adrenergic Receptor Gene in Korean Essential Hypertensives
Toxicological Research
2002 .09
-
운동선수의 베타3-아드레날린성 수용체 유전자의 Trp64Arg 다형성이 혈압, 신체조성 및 골밀도에 미치는 영향
약학회지
2005 .01
-
한방비만치료임상례중 ${\beta}3$ Adrenergic Receptor 변이율에 대한 고찰 (비만유전자보유유무에 따른 치료효과 비교)
한방비만학회지
2002 .01
-
Beta-Adrenergic Receptor Imaging
대한핵의학회 학술대회
2006 .01
-
A Bal I RFLP of Dopamine D3 Receptor Gene in Korean Hypertensives
한국환경성돌연변이·발암원학회지
2003 .03
-
Purification and Characterization of the $\beta$-Adrenergic Receptor from Rat Cerebral Cortex
한국응용약물학회 춘계학술발표논문집
1994 .01
-
Alpha 2a Adrenergic Receptor의 유전적 다형성과 멀미 감수성에 관한 연구
항공우주의학 학술대회
2007 .11
-
Association between Genetic Variation in the Human Factor Ⅶ Gene and Essential Hypertension in Korean Population
한국환경성돌연변이·발암원학회지
2001 .09
-
Practical and Effective Method for the Solubilization and Characterization of Mammalian ${\beta}$-adrenergic receptor
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
1993 .01
-
Linkage Disequilibrium of Dopamine D2 Receptor Gene in the Korean Population
Toxicological Research
2004 .03
-
SNP Analysis of the Human LDL Receptor and CETP Gene in Korean Subjects with Hypertension
한국환경성돌연변이·발암원학회지
2002 .03
-
Two Genetic Polymorphisms of the Human Lupoprotein Lupase Gene in Korean Patients with Essential Hypertension
한국환경성돌연변이·발암원학회지
2002 .03
-
한국인 본태성 고혈압군에서 에스트로젠 수용체-α 유전자에 존재하는 다형성의 분포에 관한 연구
Environmental Analysis Health and Toxicology
2005 .09
-
Genetic Variations of Eight Candidate Genes in Korean Obese Group
한국환경성돌연변이·발암원학회지
2002 .03
-
The Third Intracellular Loop of truman ${\beta}_2$-adrenergic Receptor Expressed in E. coli Decreased Binding Affinity of Isoproterenol to ${\beta}_2$-adrenergic Receptor
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
1996 .01
-
2018 Korean Society of Hypertension guidelines for the management of hypertension: part I-epidemiology of hypertension
Clinical Hypertension
2019 .01
-
한국인 집단에서 심방 나트륨 이뇨 펩티드 유전자에 존재하는 유전적 변이와 본태성 고혈압과의 관련성에 관한 연구
Toxicological Research
2006 .06
-
The Association between Codon 192 Polymorphism of Paraoxonase/arylesterase Gene and Plasma HDL-cholesterol Level in Korean Population
한국환경성돌연변이·발암원학회지
2001 .03
-
Association Study between the Genetic Variations of the Apo AⅠ-CⅢ-AⅣ Gene Cluster and Hypertension among Koreans
Toxicological Research
2002 .12
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2009-476-013751225