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논문 기본 정보

자료유형
학술저널
저자정보
남기원 (Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine) 우종진 (Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine) Hong Yooha (Department of Neurology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Republic of Korea) 모희정 (한림대학교 동탄성심병원) 조수진 (한림대학교) 임희진 (한림대학교)
저널정보
대한수면연구학회 Journal of sleep medicine Journal of sleep medicine 제21권 제2호
발행연도
2024.8
수록면
80 - 87 (8page)
DOI
10.13078/jsm.240007

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초록· 키워드

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Objectives: This study aims to examine the differences in spectral analysis of waking electroencephalography (EEG) patterns between patients with moderate to severe obstructive sleep apnea (OSA) experiencing excessive daytime sleepiness (EDS) and matched healthy participants, to gain insights into the neurophysiological underpinnings of daytime impairments. Methods: A cross-sectional analysis was conducted involving 17 patients with moderate to severe OSA confirmed by overnight polysomnography (PSG). These patients had ≥15 per hour apnea–hypopnea index (AHI) and ≥11 Epworth Sleepiness Scale (ESS). EEG recordings were captured within 30 minutes of awakening. A corresponding group of the equal number of age and sex-matched healthy participants was also analyzed for comparative purposes. Spectral analysis of quantitative EEG (qEEG) of patients with OSA compared with that of an equal number of age- and sex-matched healthy participants. Results: The analysis included 17 patients (16 males, average age 57.2 years) with moderate to severe OSA experiencing EDS (mean AHI 38.1±20.5; ESS 14.4±3.2). The patients with OSA exhibited altered sleep architecture during diagnostic PSG, significantly higher EEG delta band power in the frontal regions upon awakening after night sleep, and decreased connection of delta band in frontal area than normal participants (3.78±5.53 vs. 3.22±0.98 μV<sup>2</sup>, <i>p</i>=0.03). Conclusions: The study demonstrated difference in delta activity and connectivity in the frontal area between patients with OSA experiencing EDS and the control group. These findings suggest awakening qEEG in OSA may helpful to guide or enhance understanding of daytime functional impairment and EDS.

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