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논문 기본 정보

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학술저널
저자정보
Áine Lucey (Department of Surgical Oncology, Cork University Hospital, Cork, Ireland.) Katie Togher Julie Clifford (Department of Surgical Oncology, Cork University Hospital, Cork, Ireland.) Louise Kent (Department of Surgical Oncology, Cork University Hospital, Cork, Ireland.) Sharjeel Hussain Paul (Department of Surgical Oncology, Cork University Hospital, Cork, Ireland.) Paul Redmond (Department of Surgical Oncology, Cork University Hospital, Cork, Ireland.)
저널정보
대한갑상선-내분비외과학회 The Journal of Endocrine Surgery Journal of Endocrine Surgery 제24권 제3호
발행연도
2024.9
수록면
56 - 60 (5page)
DOI
10.16956/jes.2024.24.3.56

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Purpose: Our study aims to critically evaluate the combined use of intra-operative parathyroid hormone (ioPTH) assay testing, frozen section analysis and ex vivo specimen radio-activity using the ‘Norman 20% radio-activity rule.’ Methods: A single-centre, retrospective analysis of intra-operative adjuncts used in minimally invasive radio-guided parathyroidectomy. ioPTH assay, ex vivo specimen radio-activity using the ‘Norman 20% radio-activity rule’ and frozen section analysis were analysed to determine the sensitivity of each adjunct. The final histopathological diagnosis was also analysed. Results: The sensitivity of ioPTH assay, ‘Norman 20% radio-activity rule’ and frozen section analysis in the detection of parathyroid adenomas is 96.1%, 96.1% and 100%, respectively. When all 3 adjuncts are utilised intra-operatively, parathyroid adenomas are correctly identified in 97% of cases. Conclusion: The use of 3 intra-operative adjuncts in conjunction with one another during minimally invasive parathyroidectomy surgery leads to a high rate of the successful detection of parathyroid adenomas as confirmed by histopathological diagnosis.

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