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논문 기본 정보

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저자정보
Sameet Tariq Patel (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Anuraag Jena (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Sanjay Chandnani (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Shubham Jain (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Pankaj Nawghare (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Saurabh Bansal (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Harsh Gandhi (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Rishikesh Malokar (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Jay Chudasama (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Prasanta Debnath (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Seemily Kahmei (Department of Pathology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Rima Kamat (Department of Pathology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Sangeeta Kini (Department of Pathology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Qais Q Contractor (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India) Pravin M Rathi (Department of Gastroenterology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, India)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.22 No.3
발행연도
2024.7
수록면
310 - 318 (9page)
DOI
10.5217/ir.2023.00174

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Background/Aims: Patients of ulcerative colitis (UC) on follow-up are routinely evaluated by sigmoidoscopy. There is no prospective literature to support this practice. We assessed agreement between sigmoidoscopy and colonoscopy prospectively in patients with disease extent beyond the sigmoid colon. Methods: We conducted a prospective observational study at a tertiary care institute for agreement between sigmoidoscopy and colonoscopy. We assessed endoscopic activity using the Mayo Endoscopic Score (MES) and Ulcerative Colitis Endoscopic Index of Severity (UCEIS) and histological activity using the Nancy Index (NI), Robarts Histopathology Index (RHI), and Simplified Geboes Score (SGS). Results: Sigmoidoscopy showed a strong agreement with colonoscopy for MES and UCEIS with a kappa (κ) of 0.96 and 0.94 respectively. The misclassification rate for MES and UCEIS was 3% and 5% respectively. Sigmoidoscopy showed perfect agreement (κ = 1.00) with colonoscopy for assessment of the presence of endoscopic activity in the colon using MES ≥ 1 as activity criteria and strong agreement (κ = 0.93) using MES > 1 as activity criteria. Sigmoidoscopy showed strong agreement with colonoscopy for assessment of the presence of endoscopic activity using UCEIS (κ = 0.92). Strong agreement was observed between sigmoidoscopy and colonoscopy using NI (κ = 0.86), RHI (κ = 1.00), and SGS (κ = 0.92) for the detection of histological activity. The misclassification rate for the detection of histological activity was 2%, 0%, and 1% for NI, RHI, and SGS respectively. Conclusions: Sigmoidoscopy showed strong agreement with colonoscopy for endoscopic and histologic disease activity. Sigmoidoscopy is adequate for assessment of disease activity in patients with UC during follow-up evaluation.
#Endoscopic score #Disease severity #Biopsy #Inflammatory bowel diseases

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