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논문 기본 정보

자료유형
학술저널
저자정보
Cho Hyunjeong (Renal Division, Chungbuk National University Hospital, Cheongju, Republic of Korea.) Kwon Soon Kil (Renal Division, Chungbuk National University Hospital, Cheongju, Republic of Korea.Chungbuk National University College of Medicine, Cheongju, Republic of Korea.) Lee Seung Woo (Renal Division, Chungbuk National University Hospital, Cheongju, Republic of Korea.) Yang Yu Mi (Renal Division, Chungbuk National University Hospital, Cheongju, Republic of Korea.) Kim Hye Young (Renal Division, Chungbuk National University Hospital, Cheongju, Republic of Korea.Chungbuk National University College of Medicine, Cheongju, Republic of Korea.) Kim Sun Moon (Renal Division, Chungbuk National University Hospital, Cheongju, Republic of Korea.Chungbuk National University College of Medicine, Cheongju, Republic of Korea.) Heo Tae-Young (Department of Information and Statistics, Chungbuk National University Graduate School, Cheongju, Republic of Korea.) Seong Chang Hwan (Department of Information and Statistics, Chungbuk National University Graduate School, Cheongju, Republic of Korea.) Kim Kyeong Rok (Department of Information and Statistics, Chungbuk National University Graduate School, Cheongju, Republic of Korea.)
저널정보
전해질고혈압연구회 Electrolytes & Blood Pressure Electrolytes & Blood Pressure 제21권 제2호
발행연도
2023.12
수록면
53 - 60 (8page)
DOI
10.5049/EBP.2023.21.2.53

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초록· 키워드

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Background: Most hemodialysis (HD) patients suffer from hypertension and have a heightened cardiovascular risk. While blood pressure (BP) control is essential to end-stage kidney disease (ESKD) patients, overly stringent control can lead to intra dialytic hypotension (IDH). This study aimed to examine BP variations during and after HD to determine whether these variations correlate with IDH risk. Methods: BP measurements during dialysis were taken from 28 ESKD patients, and ambulatory BP monitoring was applied post-dialysis. Laboratory parameters and risk factors, including diabetes, coronary disease, and LV mass index, were compared between IDH and non-IDH groups using an independent t-test. Results: Of the 28 patients with an average age of 57.4 years, 16 (57.1%) had diabetes, 5 (17.9%) had coronary artery disease, and 1 (3.6%) had cerebrovascular disease. The mean systolic blood pressure (SBP) during and post-HD was 142.26 mmHg and 156.05 mmHg, respectively (p=0.0003). Similarly, the mean diastolic blood pressure (DBP) also demonstrated a significant increase, from 74.59 mmHg during HD to 86.82 mmHg post-HD (p<0.0001). Patients with IDH exhibited a more substantial SBP difference (delta SBP, 36.38 vs. 15.07 mmHg, p=0.0033; age-adjusted OR=1.58, p=0.0168) and a lower post-dialysis BUN level (12.75 vs. 18.77 mg/dL, p=0.0015; age-adjusted OR=0.76, p=0.0242). No significant variations were observed in daytime and nocturnal BP between the IDH and non-IDH groups. Conclusion: Hemodialysis patients exhibited a marked increase in post-dialysis BP and lacked a nocturnal BP dip, suggesting augmented cardiovascular risks. This highlights the importance of more stringent BP control after hemodialysis.

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