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자료유형
학술저널
저자정보
배은희 (전남대학교) 임상엽 (Korea University Ansan Hospital Ansan Republic of Korea) 김봉성 (Department of Statistics and Actuarial Science Soongsil University Seoul Republic of Korea) Han Kyungdo (Soongsil University) 오태렴 (전남대학교병원) 최홍상 (전남대학교병원) 김창성 (Chonnam National University Medical School Gwangju Republic of Korea) 마성권 (전남대학교) Kim Soo Wan (Chonnam National University)
저널정보
대한신장학회 Kidney Research and Clinical Practice Kidney Research and Clinical Practice Vol.40 No.3
발행연도
2021.9
수록면
432 - 444 (13page)
DOI
10.23876/j.krcp.21.245

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Background: Hypertension is the most important modifiable risk factor for mortality and morbidity in chronic kidney disease and cor- onary artery syndrome. The effect of hypertension prior to percutaneous coronary intervention (PCI) on the development of end-stage renal disease (ESRD) is unknown. Methods: We used nationally representative data from the Korean National Health Insurance System?140,164 subjects were en- rolled during 2010?2015; they were free of ESRD at enrolment, underwent PCI, and were followed up until 2017. Blood pressure (BP) was measured within at least 2 years prior to PCI. The primary outcome was the development of ESRD. Results: During a median follow-up of 5.4 years, 2,082 participants (1.5%) developed ESRD. The highest systolic BP group (>160 mmHg) showed a higher hazard ratio (3.69; 95% confidence interval, 2.61?5.23) than the reference group (110?119 mmHg). Simi- lar results were observed in the highest diastolic BP group (>120 mmHg), which showed a higher hazard ratio than the reference group (70?79 mmHg). However, ESRD risk showed a J-shaped relationship with baseline systolic and diastolic BP at 113 and 74 mmHg in diabetes mellitus subgroup, respectively, after adjustment for potential confounders. Conclusion: Our study showed that a high systolic or diastolic BP prior to PCI was independently associated with an increased inci- dence of ESRD.

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