지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 환경독성보건학회 Environmental Analysis Health and Toxicology Environmental Analysis Health and Toxicology Vol.39 No.2
- 발행연도
- 2024.6
- 수록면
- 138 - 154 (17page)
이용수
초록· 키워드
오류제보하기
Solid waste disposal generates leachate, a mixture of deleterious chemical, physical and microbial contaminants, which poses risk to human and wildlife health. Leachate toxicity on relative organ weight and histopathology of important viscera in mammalian body is scarce. Leachate induced toxic effects on organosomatic indices and histopathology of vital mammalian organs were investigated. Wister rats were orally exposed to 1 – 25 % of raw and simulated leachates from Aba-Eku and Olusosun landfills for 30 days. At post-exposure, organosomatic index and histoarchitectural assessment of major viscera (heart, spleen, thymus and lungs) were conducted. The physico-chemical and organic compositions of the leachates were analysed using standard protocol. The tested leachates decreased weekly and terminal body weights, and altered organosomatic index of examined viscera in rats. The histoarchitecture of the investigated viscera revealed pathologies that ranged from mild to severe degeneration, cellular infiltration, haemorrhage, congestion, necrosis, disorganization of tissues and vacuolations. Others include increased histiocytes within the bronchial associated lymphoid, lymphoid depletions, haemosiderin deposits and apoptosis were observed in the examined viscera. Physico-chemical analysis of the leachates showed different concentrations of toxic metals, PAHs and PCBs that were higher than national and international permissible limits allowed in wastewaters. The physico-chemical compositions of the leachates are capable of eliciting the observed alterations in organosomatic indices and histopathological lesions in mammalian viscera. Xenobiotic components of the leachates possibly generated free radicals and/or directly disrupted the organ architectures. These findings suggest health risk to wildlife and human population exposed to emissions from waste landfills.
목차
Abstract
Introduction
Materials and Methods
Results
Discussion
Conclusions
References
참고문헌 (39)
참고문헌 신청
Alimba CG. DNA and systemic damage induced by landfill leachates and health impacts of human exposure to landfills in Lagos and Ibadan, Nigeria [Ph.D thesis]. Nigeria: University of Ibadan, Department of Zoology; 2013, 1-258.
Alimba CG, Adewumi OO, Binuyo OM, Odeigah PGC. Wild black rats (Rattus rattus Linnaeus, 1758) as zoomonitor of genotoxicity and systemic toxicity induced by hazardous emissions from Abule Egba unsanitary landfill, Lagos, Nigeria. Environmental Science and Pollution Research 2021;28:10603-10621. https://doi.org/10.1007/s11356-020-11325-7
Siddiqua A, Hahladakis JN, Al-Attiya WAKA. An overview of the environmental pollution and health effects associated with waste landfilling and open dumping. Environ Sci Pollut Res Int 2022;29(39):58514-58536. https://doi.org/10.1007/s11356-022-21578-z
Alimba CG, Rudrashetti AP, Sivanesan S, K. Krishnamurthi K. Landfill soil leachates from Nigeria and India induced DNA damage and alterations in genes associated with apoptosis in Jurkat cell. Environmental Science and Pollution Research 2022;29:5256-5268. https://doi.org/10.1007/s11356-021-15985-x
Kurniawan TA, Lo WH, Chan GYS. Physico-chemical treatments for removal of recalcitrant contaminants from landfill leachate. Journal of Hazardous Materials 2006;129(1-3):80-100. https://doi.org/10.1016/j.jhazmat.2005.08.010
Alimba CG, Adewumi OO, Binuyo OM, Odeigah PGC. Wild black rats (Rattus rattus Linnaeus, 1758) as zoomonitor of genotoxicity and systemic toxicity induced by hazardous emissions from Abule Egba unsanitary landfill, Lagos, Nigeria. Environmental Science and Pollution Research 2021;28:10603-10621. https://doi.org/10.1007/s11356-020-11325-7
Siddiqua A, Hahladakis JN, Al-Attiya WAKA. An overview of the environmental pollution and health effects associated with waste landfilling and open dumping. Environ Sci Pollut Res Int 2022;29(39):58514-58536. https://doi.org/10.1007/s11356-022-21578-z
Alimba CG, Rudrashetti AP, Sivanesan S, K. Krishnamurthi K. Landfill soil leachates from Nigeria and India induced DNA damage and alterations in genes associated with apoptosis in Jurkat cell. Environmental Science and Pollution Research 2022;29:5256-5268. https://doi.org/10.1007/s11356-021-15985-x
Kurniawan TA, Lo WH, Chan GYS. Physico-chemical treatments for removal of recalcitrant contaminants from landfill leachate. Journal of Hazardous Materials 2006;129(1-3):80-100. https://doi.org/10.1016/j.jhazmat.2005.08.010
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