지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.3
- 수록면
- 162 - 178 (17page)
- DOI
- 10.14245/ns.2347342.671
이용수
초록· 키워드
오류제보하기
Proteoglycans through their sulfated glycosaminoglycans regulate cell-matrix signaling during tissue development, regeneration, and degeneration processes. Large extracellular proteoglycans such as aggrecan, versican, and perlecan are especially important for the structural integrity of the intervertebral disc and cartilage during development. In these tissues, proteoglycans are responsible for hydration, joint flexibility, and the absorption of mechanical loads. Loss or reduction of these molecules can lead to disc degeneration and skeletal dysplasia, evident from loss of disc height or defects in skeletal development respectively. In this review, we discuss the common proteoglycans found in the disc and cartilage and elaborate on various murine models and skeletal dysplasias in humans to highlight how their absence and/or aberrant expression causes accelerated disc degeneration and developmental defects.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Proteoglycan Dysfunction as a Key Hallmark of Intervertebral Disc Degeneration: Commentary on “Proteoglycan Dysfunction: A Common Link Between Intervertebral Disc Degeneration and Skeletal Dysplasia”
Neurospine
2024 .03
-
Clinical management and emerging therapies of FGFR3-related skeletal dysplasia in childhood
Annals of Pediatirc Endocrinology & Metabolism
2022 .06
-
Molecular Diagnosis for Skeletal Dysplasia in Korea
Journal of mucopolysaccharidosis and rare disease
2016 .01
-
Current strategies for treatment of intervertebral disc degeneration: substitution and regeneration possibilities
생체재료학회지
2017 .12
-
Far lateral lumbar disc extrusion in a dachshund dog
Korean Journal of Veterinary Research(대한수의학회지)
2019 .10
-
Proteomic Signatures of Healthy Intervertebral Discs From Organ Donors: A Comparison With Previous Studies on Discs From Scoliosis, Animals, and Trauma
Neurospine
2020 .01
-
Experience of Skeletal Dysplasia in a Tertiary Referral Hospital in India
Journal of mucopolysaccharidosis and rare disease
2016 .01
-
Finite Element Analysis of Stress Distribution and Range of Motion in Discogenic Back Pain
Neurospine
2024 .06
-
Actions of Prostaglandins on Human Nucleus Pulposus Metabolism Inferred by Cyclooxygenase 2 Inhibition of Cytokine Activated Cells
Neurospine
2020 .01
-
Commentary on “Gene Therapy Approach for Intervertebral Disc Degeneration: An Update”
Neurospine
2020 .01
-
Morphometric Study of the Lumbar Posterior Longitudinal Ligament
대한신경외과학회지
2018 .01
-
Fetal Skeletal Staining Method and Atlas of Mice, Rats and Rabbits for Non-Clinical Developmental Toxicity Study
한국실험동물학회 학술발표대회 논문집
2015 .08
-
Proteomic Signature of Nucleus Pulposus in Fetal Intervertebral Disc
Asian Spine Journal
2020 .01
-
Evaluation of the resection effi ciency and safety of an enhanced power plasma generator using cadaveric intervertebral discs
Biomedical Engineering Letters (BMEL)
2023 .02
-
대학생의 DISC 행동유형에 따른 스트레스 지각, 대처, 대인관계만족도에 관한 연구
스트레스硏究
2019 .12
-
간호대학생의 DISC 행동유형에 따른 임상실습스트레스와 정신건강
의료커뮤니케이션
2018 .01
-
Acute Malocclusion Related to Posterior Disc Displacement According to Complete Disc Tearing: Two Case Reports
Journal of Oral Medicine and Pain
2024 .06
-
Mini-partial lateral corpectomy and hemilaminectomy for the treatment of heavily protruded thoracolumbar intervertebral disc in small dogs
Korean Journal of Veterinary Research(대한수의학회지)
2020 .02
-
Hypoxia Regulates the Extracellular Matrix via Mitogen-Activated Protein Kinases Pathway in Cells Retrieved from the Human Intervertebral Disc
Yonsei Medical Journal
2021 .01
-
Human Tissue-Engineered Skeletal Muscle: A Tool for Metabolic Research
Endocrinology and Metabolism
2022 .06
최근 본 자료
댓글(0)
0