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논문 기본 정보

자료유형
학술저널
저자정보
Jongpeeti Wudtisan Prapaporn Suprasert (Division of Gynecologic Oncology Department of Obstetrics and Gynecology Chiang Mai University Fac)
저널정보
대한산부인과학회 Obstetrics & Gynecology Science Obstetrics & Gynecology Science 제66권 제1호
발행연도
2023.1
수록면
34 - 41 (8page)
DOI
https://doi.org/10.5468/ogs.22241

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초록· 키워드

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ObjectiveTo evaluate the effect of paclitaxel and platinum-based chemotherapy (PT) on micturition symptoms. MethodsAll gynecologic cancer patients who were assigned to receive the PT regimen and understood the Thai languagewere invited to participate in this study. The exclusion criteria were as follows: abnormal urinary symptoms, retainedurinary catheter or percutaneous nephrostomy, anticholinergic drug use, or scheduled to receive radiation therapyafter the completion of chemotherapy. The participants were interviewed using three Thai validated questionnaires,the incontinence impact questionnaire-short form, urogenital distress inventory short form, and Sandvik score, onthe day before receiving the first cycle of chemotherapy (pre-treatment), on the day before receiving the 4th cycle(mid-treatment), and 46 weeks after completing 69 cycles (post-treatment). The scores at the three time points werecompared. Patients who received less than three cycles were not included in the analysis. ResultsOne hundred and ten patients were included in this study. There were significant differences in the medianquestionnaire scores at the three time points for both carboplatin plus paclitaxel and cisplatin plus paclitaxel. However, when using a pairwise difference between the two treatment protocols, there were no significant changesin the score from pre-treatment to post-treatment. ConclusionThe PT regimen has an impact on micturition symptoms during chemotherapy which recover after treatmentcompletion.

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