지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.5
- 수록면
- 117 - 121 (5page)
이용수
초록· 키워드
오류제보하기
Vitiligo has been considered an unexplained paradoxical phenomenon during biologics use.
Herein, we report an adult case of progression of pre-existing vitiligo during secukinumab treatment for psoriasis, and we also examined the immunohistochemical changes in rela- tion to biologics use. He was being administered monthly secukinumab of 300 mg dose for 2 years, and all psoriatic lesions were cleared, but pre-existing hypopigmented lesions became more distinct and larger than before unlike when using adalimumab. A skin biopsy of the hypopigmented lesion showed loss of epidermal melanocytes and absence of gp100 immune activities, and he was finally diagnosed with progression of pre-existing vitiligo.
Immunohistochemical staining of vitiligo lesion showed decrease in interleukin-17 and tu- mor necrosis factor-α and increase in CD8+ T cells, interferon-γ, and CXCL10 after the use of secukinumab. In this study, we suggest that biologics-induced cytokine imbalance play a critical role in vitiligo progression in patients with chronic inf lammatory diseases, includ- ing psoriasis.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
건선의 생물학제제 교체치료
대한건선학회지
2018 .01
-
중등도와 중증의 건선환자에서 생물학제제 치료 후 치료 만족도에 대한 평가
대한건선학회지
2021 .12
-
Secukinumab Response in Korean Patients with Moderate to Severe Plaque-Type Psoriasis Irrespective of Previous Biologic Use: 1-Year Experience at a Single Center
Annals of Dermatology
2020 .01
-
Clinical Characteristics of Psoriasis for Initiation of Biologic Therapy: A Cluster Analysis
Annals of Dermatology
2023 .04
-
안면 백반증 치료 평가를 위한 딥러닝 기반 자동화 분석 시스템 개발
의공학회지
2024 .04
-
Which areas are still left in biologics responsive Korean patients with moderate to severe plaque psoriasis
Annals of Dermatology
2023 .02
-
Erythrodermic Psoriasis Treated with Golimumab: A Case Report
Annals of Dermatology
2015 .01
-
건선 연구에서 건선 피부 모델의 역할
대한건선학회지
2018 .01
-
Prevalence of Psoriasis in Korea: A Population-Based Epidemiological Study Using the Korean National Health Insurance Database
Annals of Dermatology
2017 .01
-
건선 환자에서 생물학적제제 투여 중 재활성화된 잠복결핵 1예
대한건선학회지
2021 .12
-
만성신부전이 동반된 판상건선 환자의 생물학적제제 치료 3예
대한건선학회지
2021 .06
-
Ustekinumab과 Guselkumab에 치료저항성을 보인 건선 1예
대한건선학회지
2019 .01
-
Psoriasis flares after COVID-19 vaccination: adherence to biologic therapy reduces psoriasis exacerbations: a case-control study
Clinical and Experimental Vaccine Research
2023 .01
-
Development of Vitiligo during Treatment with Adalimumab: A Plausible or Paradoxical Response?
Annals of Dermatology
2015 .01
-
코로나바이러스감염증-19(COVID-19)와 건선 치료에 대한 고찰
대한건선학회지
2020 .01
-
Prevalence of Vitiligo and Associated Comorbidities in Korea
Yonsei Medical Journal
2015 .01
-
Validity of Diagnostic Codes for Identification of Psoriasis Patients in Korea
Annals of Dermatology
2020 .01
-
Basic Therapeutic Approach for Patients with Plaque Psoriasis: Korean Expert Consensus Using the Modified Delphi Method
Annals of Dermatology
2023 .06
-
Real-World Outcomes of Adalimumab Treatment for Moderate and Severe Psoriasis in Korean Patients (RAPSODI Study)
Annals of Dermatology
2023 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0