지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Not every psoriasis patient who prescribed biologics for psoriasis shows clinical improvement defined by Psoriasis Area and Severity Index (PASI) 75. Clinicians should consider the switching of one biologic to different one to improve patient’s psoriasis. We can meet two clinical situations as initial non-responder and loss of effectiveness after long term use. Initial non-responder shows less than 75% improvement of PASI at primary endpoint. It is better to consider to use biologics of different mechanism of action. Loss of effectiveness after long term use includes biologics fatigue. The other biologics than previously used one can be considered for this patient. Biologic fatigue phenomenon is commonly developed when we use biologic for long term period, we do not know the exact character and its proper role in the loss of effectiveness. Recently, newer biologics are coming and will be in market competitively, clinicians will have good tools to cope with biologics failure patients.
목차
등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
윤상웅 / 2015 / Comparison of Treatment Goals for Moderate-to-Severe Psoriasis between Korean Dermatologists and the European Consensus Report / Annals of Dermatology 27(2):184~189
최종원 / 2017 / The Advantage of Cyclosporine A and Methotrexate Rotational Therapy in Long-Term Systemic Treatment for Chronic Plaque Psoriasis in a Real World Practice / Annals of Dermatology 29(1):55~60
Nast A / 2012 / S2-guidelines on the treatment of psoriasis vulgaris (English version). Update / J Dtsch Dermatol Ges 10(suppl2):S1~S95
Levin EC / 2014 / Biologics fatigue in psoriasis / J Dermatolog Treat 25:78~82
Hsu L / 2014 / Antidrug antbodies in psoriasis:a systematic review / Br J Dermatol 170:261~273
최종원 / 2017 / The Advantage of Cyclosporine A and Methotrexate Rotational Therapy in Long-Term Systemic Treatment for Chronic Plaque Psoriasis in a Real World Practice / Annals of Dermatology 29(1):55~60
Nast A / 2012 / S2-guidelines on the treatment of psoriasis vulgaris (English version). Update / J Dtsch Dermatol Ges 10(suppl2):S1~S95
Levin EC / 2014 / Biologics fatigue in psoriasis / J Dermatolog Treat 25:78~82
Hsu L / 2014 / Antidrug antbodies in psoriasis:a systematic review / Br J Dermatol 170:261~273
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