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논문 기본 정보

자료유형
학술저널
저자정보
Choi Sooin (Department of Laboratory Medicine and Genetics Soonchunhyang University Bucheon Hospital Soonchunhyang University College of Medicine Bucheon Korea) Choi Soo Jeong (Division of Nephrology Department of Internal Medicine Soonchunhyang University Bucheon Hospital Soonchunhyang University College of Medicine Bucheon Korea) Shin Jeong Won (Department of Laboratory Medicine Soonchunhyang University Seoul Hospital Soonchunhyang University College of Medicine Seoul Korea) Yoon Young Ahn (Department of Laboratory Medicine Soonchunhyang University Cheonan Hospital Soonchunhyang University College of Medicine Cheonan Korea)
저널정보
대한진단검사의학회 Annals of Laboratory Medicine Annals of Laboratory Medicine 제43권 제2호
발행연도
2023.3
수록면
187 - 195 (9page)
DOI
10.3343/alm.2023.43.2.187

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Background: The selective leukoreduction protocol (SLP) is limited in that patients who require it can be overlooked. We estimated SLP compliance (SLPC) using the Observational Medical Outcomes Partnership common data model (CDM). Methods: Patients were classified into eight groups: pre- and post-hematology disease (A and B), pre- and post-solid organ transplantation (C and D), solid cancer (E), immunodeficiency (F), anticancer therapy (G), and cardiovascular surgery (H). We examined the red blood cell (RBC) transfusion history from three hospital datasets comprising approximately three million patients over 20 years using CDM-based analysis. SLPC was calculated as the percentage of patients who received only leukoreduced RBCs in total patients transfused RBCs. Results: In total, 166,641 patients from three hospitals were enrolled in this study. From 2001 to 2021, SLPC in all groups, except H, tended to increase, although there were differences among the hospitals. Based on the most recent values (2017–2021), the SLPC in groups A, B, D, and G was maintained at ≥75% until 1,095 days before or after diagnosis or treatment. Groups E, F, and H had < 50% SLPC one day after diagnosis and treatment. Conclusions: CDM analysis supports the review of large datasets for SLPC evaluation. Although SLPC tended to improve in most patient groups, additional education and monitoring are needed for groups that continue to show low SLPC.

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