지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2023.4
- 수록면
- 1 - 12 (12page)
- DOI
- 10.1038/s12276-023-00981-7
이용수
초록· 키워드
오류제보하기
Cells produce multiple mRNAs through alternative splicing, which ensures proteome diversity. Because most human genes undergo alternative splicing, key components of signal transduction pathways are no exception. Cells regulate various signal transduction pathways, including those associated with cell proliferation, development, differentiation, migration, and apoptosis. Since proteins produced through alternative splicing can exhibit diverse biological functions, splicing regulatory mechanisms affect all signal transduction pathways. Studies have demonstrated that proteins generated by the selective combination of exons encoding important domains can enhance or attenuate signal transduction and can stably and precisely regulate various signal transduction pathways. However, aberrant splicing regulation via genetic mutation or abnormal expression of splicing factors negatively affects signal transduction pathways and is associated with the onset and progression of various diseases, including cancer. In this review, we describe the effects of alternative splicing regulation on major signal transduction pathways and highlight the significance of alternative splicing.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
A sequence-based deep learning model for Alternative splicing prediction
제어로봇시스템학회 국내학술대회 논문집
2018 .05
-
Experimental study on flexural behavior of splicing concrete-filled GFRP tubular composite members connected with steel bars
Steel and Composite Structures, An International Journal
2015 .01
-
정형 언어 대상의 RNA splicing 연산자
한국정보과학회 학술발표논문집
2022 .12
-
Efficient Labeling of Transmembrane Proteins Based on Engineered Split-Intein Mediated Protein Trans-splicing
한국생물공학회 학술대회
2015 .10
-
Endocytic Movement and Cell Signal Transduction
한국생물공학회 학술대회
2018 .10
-
Tau mis-splicing in the pathogenesis of neurodegenerative disorders
BMB Reports
2016 .01
-
SR proteins regulate V6 exon splicing of CD44 pre-mRNA
BMB Reports
2016 .01
-
Splicing Prediction Using Deep Learning
제어로봇시스템학회 각 지부별 자료집
2019 .01
-
RRM but not the Asp/Glu domain of hnRNP C1/C2 is required for splicing regulation of Ron exon 11 pre-mRNA
BMB Reports
2019 .01
-
Tailored antisense oligonucleotides designed to correct aberrant splicing reveal actionable groups of mutations for rare genetic disorders
Experimental and Molecular Medicine
2024 .08
-
Engineering Cytokine Receptors for Applications in Regenerative Medicine and Drug Discovery
한국생물공학회 학술대회
2017 .04
-
Construction and Analysis of Regulatory Networks
한국생물공학회 학술대회
2016 .10
-
Enabling Artificial Intelligence for Genome Sequence Analysis
대한전자공학회 학술대회
2022 .04
-
동시 발생 행렬의 특성함수 모멘트를 이용한 접합 영상 검출
대한임베디드공학회논문지
2015 .01
-
SRSF2 directly inhibits intron splicing to suppresses cassette exon inclusion
BMB Reports
2017 .01
-
Assembly of platforms for signal transduction in the new era: dimerization, helical filament assembly, and beyond
Experimental and Molecular Medicine
2020 .01
-
알루미늄 허니콤 코어 접합부 유무에 따른 샌드위치 복합재의 물성 시험
대한기계학회 춘추학술대회
2022 .11
-
Human Genes with a Greater Number of Transcript Variants Tend to Show Biological Features of Housekeeping and Essential Genes
한국생물공학회 학술대회
2015 .10
-
Membrane Dynamics and Signal Transduction
한국생물공학회 학술대회
2017 .10
-
마코프 특징을 이용하는 고속 위조 영상 검출 알고리즘
전기전자학회논문지
2018 .06
이 논문의 저자 정보
최근 본 자료
댓글(0)
0