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논문 기본 정보

자료유형
학술저널
저자정보
Jangho Park (Osan Hankook Hospital) Sang-Jae Park (National Cancer Center) Sung-Sik Han (National Cancer Center) Hyeong Min Park (National Cancer Center) Jihye Yu (National Cancer Center) Boram Park (Samsung Medical Center) Young-Woo Kim (National Cancer Center) Sun-Whe Kim (Chung-Ang University Gwangmyeong Hospital)
저널정보
대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.105 No.2
발행연도
2023.8
수록면
82 - 90 (9page)

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Purpose: Perioperative transfusion is reported to be an independent risk factor not only for postoperative complications but also for early recurrence of periampullary carcinoma after pancreaticoduodenectomy (PD). The purpose of this study was to evaluate the safety and efficacy of ferric carboxymaltose (FCM) in reducing the need for perioperative transfusion in iron deficiency anemia patients scheduled for PD.
Methods: Twenty-two male patients (hemoglobin [Hb] 7 to <13 g/dL) and 18 female patients (Hb 7 to <12 g/dL) were enrolled in the study group and administered FCM 1–3 weeks before PD. The perioperative transfusion rate was the primary endpoint; morbidity, length of postoperative hospital stay, change in hematological parameters after FCM injection, and adverse effects of FCM were also investigated.
Results: The perioperative transfusion rate of the study group was 22.5% (9 of 40). Hb level was significantly higher on the day of the operation compared to baseline (P < 0.001). Levels of Hb, transferrin saturation, and ferritin were higher at the follow-up compared to baseline (P = 0.008, P = 0.033, and P < 0.001, respectively).
Conclusions FCM administration was associated with a reduced need for perioperative transfusion and can safely stabilize hematological parameters.

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