지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.12
- 수록면
- 98 - 101 (4page)
- DOI
- https://doi.org/10.12701/yujm.2015.32.2.98
이용수
초록· 키워드
오류제보하기
Bronchiolitis obliterans (BO), which is associated with graft-versus-host disease after allogenic hematopoietic stem cell transplantation, is a major obstacle to survival after bone marrow transplantation due to its gradual progress, eventually leading to respiratory failure. Pumpless extracorporeal interventional lung assist (iLA) is effective in treatment of reversible hypercapnic respiratory failure. In this paper, we present a 23-year-old female patient who underwent allogeneic peripheral blood stem cell transplantation (PBSCT) for acute lymphocytic leukemia. After 6 months, she complained of shortness of breath and was diagnosed with BO. Five months later, she developed an upper respiratory tract infection that worsened her BO and caused life-threatening hypercapnia. Since mechanical ventilation failed to eliminate CO2 effectively, iLA was applied as rescue therapy. Her hypercapnia and respiratory acidosis showed significant improvement within a few hours, and she was successfully weaned off iLA after 12 days. This is the first case report of iLA application for temporarily aggravated hypercapnia of PBSCT-associated BO followed by successful weaning. This rescue therapy should be considered in ventilator-refractory reversible hypercapnia in BO patients.
목차
등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Ditschkowski M / 2013 / Bronchiolitis obliterans after allogeneic hematopoietic SCT: further insight--new perspectives? / Bone Marrow Transplant 48:1224~1229
Chien JW / 2010 / Bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation-an increasingly recognized manifestation of chronic graft-versus-host disease / Biol Blood Marrow Transplant 16(1 Suppl):S106~S114
Bartosik W / 2011 / The Novalung interventional lung assist as bridge to lung transplantation for self-ventilating patients-initial experience / Interact Cardiovasc Thorac Surg 13:198~200
Fischer S / 2006 / Bridge to lung transplantation with the novel pumpless interventional lung assist device NovaLung / J Thorac Cardiovasc Surg 131:719~723
이영석 / 2012 / 침습적 기계환기로도 호전이 되지 않는 치료불응성 천식 환자에서 Interventional Lung Assist를 적용한 1예 -증례 보고- / Acute and Critical Care 27(2):108~110
Chien JW / 2010 / Bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation-an increasingly recognized manifestation of chronic graft-versus-host disease / Biol Blood Marrow Transplant 16(1 Suppl):S106~S114
Bartosik W / 2011 / The Novalung interventional lung assist as bridge to lung transplantation for self-ventilating patients-initial experience / Interact Cardiovasc Thorac Surg 13:198~200
Fischer S / 2006 / Bridge to lung transplantation with the novel pumpless interventional lung assist device NovaLung / J Thorac Cardiovasc Surg 131:719~723
이영석 / 2012 / 침습적 기계환기로도 호전이 되지 않는 치료불응성 천식 환자에서 Interventional Lung Assist를 적용한 1예 -증례 보고- / Acute and Critical Care 27(2):108~110
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