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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.2
- 수록면
- 95 - 104 (10page)
- DOI
- 10.14348/molcells.2015.2298
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초록· 키워드
오류제보하기
The development of cancer has been an extensively researched topic over the past few decades. Although great strides have been made in cancer prevention, diagnosis, and treatment, there is still much to be learned about cancer’s micro-environmental mechanisms that contribute to cancer formation and aggressiveness. Macrophages, lymphocytes which originate from monocytes, are involved in the inflammatory response and often dispersed to areas of infection to fight harmful antigens and mutated cells in tissues. Macrophages have a plethora of roles including tissue development and repair, immune system functions, and inflammation. We discuss various pathways by which macrophages get activated, various approaches that can regulate the function of macrophages, and how these approaches can be helpful in developing new cancer therapies.
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등록된 정보가 없습니다.
참고문헌 (132)
참고문헌 신청
Akaogi, J. / 2004 / Prostaglandin E2 receptors EP2 and EP4are up-regulated in peritoneal macrophages and joints of pristane-treated mice and modulate TNF-alpha and IL-6 production / J. Leukoc. Biol 76:227~236
Allavena, P. / 2008 / The inflammatory micro-environment in tumor progression : the role of tumor-associated macrophages / Crit. Rev. Oncol. Hematol 66:1~9
Bayne, L. J. / 2012 / Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer / Cancer Cell 21:822~835
Beatty, G. L. / 2011 / CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans / Science 331:1612~1616
Biswas, S. K. / 2010 / Macrophage plasticity and interaction with lymphocyte subsets : cancer as a paradigm / Nat. Immunol 11:889~896
Allavena, P. / 2008 / The inflammatory micro-environment in tumor progression : the role of tumor-associated macrophages / Crit. Rev. Oncol. Hematol 66:1~9
Bayne, L. J. / 2012 / Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer / Cancer Cell 21:822~835
Beatty, G. L. / 2011 / CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans / Science 331:1612~1616
Biswas, S. K. / 2010 / Macrophage plasticity and interaction with lymphocyte subsets : cancer as a paradigm / Nat. Immunol 11:889~896
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